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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: WDR5B All Species: 18.18
Human Site: Y239 Identified Species: 33.33
UniProt: Q86VZ2 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.33
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VZ2 NP_061942.2 330 36338 Y239 N T L K L W D Y S R G R C L K
Chimpanzee Pan troglodytes Q5IS43 410 46712 K306 S E T K K S G K P G P F L L S
Rhesus Macaque Macaca mulatta XP_001112263 330 36273 Y239 N T L K L W D Y S R G R C L K
Dog Lupus familis XP_850117 334 36428 Y243 N T L K L W D Y S K G K C L K
Cat Felis silvestris
Mouse Mus musculus Q9D7H2 328 36014 S238 T L K L W D Y S R G R C L K T
Rat Rattus norvegicus Q4V8C4 328 36030 S238 T L K L W D Y S R G R C L K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506016 334 36605 Y243 N T L K L W D Y S K G K C L K
Chicken Gallus gallus Q9PTR5 410 46646 K306 S E T K K S G K P G P F L L S
Frog Xenopus laevis Q5FWQ6 415 45899 L291 S C K L W D S L N G K C V A T
Zebra Danio Brachydanio rerio Q803D2 410 46511 K306 S E N K K S G K P G P F L L S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V3J8 361 39023 Y270 N T L K L W D Y S K G K C L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q17963 376 40375 F285 S T L K L W D F S K G K T L K
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38123 315 34735 R225 C I G G C V V R T F Q V Q P L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 28.5 97.5 82 N.A. 82.7 83.9 N.A. 85 28.7 23.8 27.7 N.A. 73.6 N.A. 56.9 N.A.
Protein Similarity: 100 46 99.6 88.9 N.A. 93 93.3 N.A. 90.4 46.8 41.2 45.6 N.A. 80.8 N.A. 71.2 N.A.
P-Site Identity: 100 13.3 100 86.6 N.A. 0 0 N.A. 86.6 13.3 0 13.3 N.A. 86.6 N.A. 66.6 N.A.
P-Site Similarity: 100 20 100 100 N.A. 0 0 N.A. 100 20 13.3 20 N.A. 100 N.A. 93.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 31.5 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 50 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % A
% Cys: 8 8 0 0 8 0 0 0 0 0 0 24 39 0 0 % C
% Asp: 0 0 0 0 0 24 47 0 0 0 0 0 0 0 0 % D
% Glu: 0 24 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 8 0 24 0 0 0 % F
% Gly: 0 0 8 8 0 0 24 0 0 47 47 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 24 70 24 0 0 24 0 31 8 31 0 16 47 % K
% Leu: 0 16 47 24 47 0 0 8 0 0 0 0 39 70 8 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 39 0 8 0 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 24 0 24 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 8 0 8 0 0 % Q
% Arg: 0 0 0 0 0 0 0 8 16 16 16 16 0 0 0 % R
% Ser: 39 0 0 0 0 24 8 16 47 0 0 0 0 0 24 % S
% Thr: 16 47 16 0 0 0 0 0 8 0 0 0 8 0 24 % T
% Val: 0 0 0 0 0 8 8 0 0 0 0 8 8 0 0 % V
% Trp: 0 0 0 0 24 47 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 16 39 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _