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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SGMS1 All Species: 10.91
Human Site: S59 Identified Species: 18.46
UniProt: Q86VZ5 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VZ5 NP_671512.1 419 49208 S59 K P P L C R V S S D N G Q R L
Chimpanzee Pan troglodytes XP_001161788 413 48640 E65 Q R L L D M I E T L K M E H H
Rhesus Macaque Macaca mulatta XP_001096809 478 54827 V124 S P P L E I K V L G D I K R L
Dog Lupus familis XP_534777 413 48058 E65 Q R L L D L I E T L K V E Q H
Cat Felis silvestris
Mouse Mus musculus Q8VCQ6 419 49298 S59 K P P L Y R V S S D N G Q R L
Rat Rattus norvegicus Q7TSX5 419 48996 S59 K P P L C R V S S D N G Q R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506553 390 44251 L61 S D N G Q R L L D M I E T L K
Chicken Gallus gallus Q7T3T4 417 48996 E69 Q Q L L H M I E T L K M A H H
Frog Xenopus laevis NP_001084610 412 48134 M63 N G R H L L E M I E T L K I E
Zebra Danio Brachydanio rerio NP_001071082 404 46969 R58 R V T S D G G R L L L E K I E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VS60 600 67045 T95 G E V L L S L T E E D V R D M
Honey Bee Apis mellifera XP_392299 397 45005 A58 R Q P L L P G A P T K G K D K
Nematode Worm Caenorhab. elegans Q20696 483 54970 C63 D P P V S I N C L G D I K K I
Sea Urchin Strong. purpuratus XP_783607 399 45476 K60 M K V L G D I K R L I R Q I D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98 35.3 91.6 N.A. 97.6 97.3 N.A. 60.3 84.7 70.8 65.8 N.A. 28.5 38.4 26.5 38.1
Protein Similarity: 100 98.5 52.5 94.5 N.A. 98.5 98.3 N.A. 67.5 91.4 82 78.5 N.A. 42.8 55.8 47.8 57.2
P-Site Identity: 100 6.6 33.3 6.6 N.A. 93.3 100 N.A. 6.6 6.6 0 0 N.A. 6.6 20 13.3 13.3
P-Site Similarity: 100 33.3 46.6 40 N.A. 93.3 100 N.A. 13.3 26.6 13.3 13.3 N.A. 46.6 40 46.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % A
% Cys: 0 0 0 0 15 0 0 8 0 0 0 0 0 0 0 % C
% Asp: 8 8 0 0 22 8 0 0 8 22 22 0 0 15 8 % D
% Glu: 0 8 0 0 8 0 8 22 8 15 0 15 15 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 8 0 8 8 8 15 0 0 15 0 29 0 0 0 % G
% His: 0 0 0 8 8 0 0 0 0 0 0 0 0 15 22 % H
% Ile: 0 0 0 0 0 15 29 0 8 0 15 15 0 22 8 % I
% Lys: 22 8 0 0 0 0 8 8 0 0 29 0 36 8 15 % K
% Leu: 0 0 22 72 22 15 15 8 22 36 8 8 0 8 29 % L
% Met: 8 0 0 0 0 15 0 8 0 8 0 15 0 0 8 % M
% Asn: 8 0 8 0 0 0 8 0 0 0 22 0 0 0 0 % N
% Pro: 0 36 43 0 0 8 0 0 8 0 0 0 0 0 0 % P
% Gln: 22 15 0 0 8 0 0 0 0 0 0 0 29 8 0 % Q
% Arg: 15 15 8 0 0 29 0 8 8 0 0 8 8 29 0 % R
% Ser: 15 0 0 8 8 8 0 22 22 0 0 0 0 0 0 % S
% Thr: 0 0 8 0 0 0 0 8 22 8 8 0 8 0 0 % T
% Val: 0 8 15 8 0 0 22 8 0 0 0 15 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _