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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CYP4Z1 All Species: 2.42
Human Site: S241 Identified Species: 5.93
UniProt: Q86W10 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86W10 NP_835235.1 505 59086 S241 D L V F K F S S Q G Q I F S K
Chimpanzee Pan troglodytes XP_001141506 510 58133 A248 T I Y S L T S A G R W T H R A
Rhesus Macaque Macaca mulatta XP_001109135 519 59279 T248 T I Y S L T S T G R W T H R A
Dog Lupus familis XP_539622 507 58744 Q243 I I F K F S P Q G H R L Q E L
Cat Felis silvestris
Mouse Mus musculus O88833 509 58321 N247 T I Y K L S S N G R L A K Q A
Rat Rattus norvegicus Q8K4D6 507 58555 S241 H D I I F K L S P K G H C F Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520882 506 58357 L242 F I Y W L S P L G R C F R Q A
Chicken Gallus gallus XP_422455 504 57538 S240 A F Y D L T H S S R E F Q D A
Frog Xenopus laevis NP_001091126 516 59853 L244 V I F Y L S P L G F R F R R A
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q27589 501 57896 K238 T E A K R Q D K A I K V M H D
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 55.4 50.8 55.6 N.A. 48.5 53.4 N.A. 49.5 49.1 50.7 N.A. N.A. 32.2 N.A. N.A. N.A.
Protein Similarity: 100 71.9 68.2 73.1 N.A. 70.1 74.3 N.A. 70.3 67.5 66.8 N.A. N.A. 52.8 N.A. N.A. N.A.
P-Site Identity: 100 6.6 6.6 0 N.A. 6.6 6.6 N.A. 0 6.6 0 N.A. N.A. 0 N.A. N.A. N.A.
P-Site Similarity: 100 20 20 20 N.A. 20 20 N.A. 13.3 13.3 20 N.A. N.A. 20 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 10 0 0 0 0 10 10 0 0 10 0 0 60 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % C
% Asp: 10 10 0 10 0 0 10 0 0 0 0 0 0 10 10 % D
% Glu: 0 10 0 0 0 0 0 0 0 0 10 0 0 10 0 % E
% Phe: 10 10 20 10 20 10 0 0 0 10 0 30 10 10 0 % F
% Gly: 0 0 0 0 0 0 0 0 60 10 10 0 0 0 0 % G
% His: 10 0 0 0 0 0 10 0 0 10 0 10 20 10 0 % H
% Ile: 10 60 10 10 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 0 0 0 30 10 10 0 10 0 10 10 0 10 0 10 % K
% Leu: 0 10 0 0 60 0 10 20 0 0 10 10 0 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % M
% Asn: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 30 0 10 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 10 0 10 10 0 10 0 20 20 10 % Q
% Arg: 0 0 0 0 10 0 0 0 0 50 20 0 20 30 0 % R
% Ser: 0 0 0 20 0 40 40 30 10 0 0 0 0 10 0 % S
% Thr: 40 0 0 0 0 30 0 10 0 0 0 20 0 0 0 % T
% Val: 10 0 10 0 0 0 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 10 0 0 0 0 0 0 20 0 0 0 0 % W
% Tyr: 0 0 50 10 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _