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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NLRP8
All Species:
4.55
Human Site:
Y44
Identified Species:
20
UniProt:
Q86W28
Number Species:
5
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W28
NP_789781.2
1048
119430
Y44
C
E
N
G
V
M
L
Y
M
R
N
V
S
H
E
Chimpanzee
Pan troglodytes
XP_512922
1058
120577
Y44
C
E
N
G
V
M
L
Y
M
R
N
V
S
H
E
Rhesus Macaque
Macaca mulatta
B0FPE9
1035
118173
A55
K
A
D
H
V
D
L
A
T
L
M
I
D
F
N
Dog
Lupus familis
XP_853947
1032
118667
Q44
R
P
R
P
G
S
V
Q
I
T
W
D
Q
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6B966
993
113342
K44
N
I
F
T
M
W
Y
K
T
S
L
H
G
E
F
Rat
Rattus norvegicus
Q63035
880
98190
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.5
28.9
59
N.A.
31
23.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.1
46.5
72.5
N.A.
48.2
39.7
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
0
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
26.6
20
N.A.
6.6
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
17
0
0
0
0
0
17
0
0
0
0
0
0
0
% A
% Cys:
34
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
17
0
0
0
0
0
17
17
0
0
% D
% Glu:
0
34
0
0
0
0
0
0
0
0
0
0
0
17
34
% E
% Phe:
0
0
17
0
0
0
0
0
0
0
0
0
0
17
17
% F
% Gly:
0
0
0
34
17
0
0
0
0
0
0
0
17
0
0
% G
% His:
0
0
0
17
0
0
0
0
0
0
0
17
0
34
0
% H
% Ile:
0
17
0
0
0
0
0
0
17
0
0
17
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
17
0
0
0
0
0
0
17
% K
% Leu:
0
0
0
0
0
0
50
0
0
17
17
0
0
0
0
% L
% Met:
0
0
0
0
17
34
0
0
34
0
17
0
0
0
0
% M
% Asn:
17
0
34
0
0
0
0
0
0
0
34
0
0
0
17
% N
% Pro:
0
17
0
17
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
0
0
17
0
0
% Q
% Arg:
17
0
17
0
0
0
0
0
0
34
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
17
0
0
0
17
0
0
34
0
0
% S
% Thr:
0
0
0
17
0
0
0
0
34
17
0
0
0
0
0
% T
% Val:
0
0
0
0
50
0
17
0
0
0
0
34
0
17
0
% V
% Trp:
0
0
0
0
0
17
0
0
0
0
17
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
17
34
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _