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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TPRA1
All Species:
16.36
Human Site:
S221
Identified Species:
36
UniProt:
Q86W33
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W33
NP_001129525.1
373
41053
S221
T
P
L
K
E
R
I
S
L
P
S
R
R
S
F
Chimpanzee
Pan troglodytes
XP_001136957
373
41062
S221
T
P
L
K
E
R
I
S
L
P
S
R
R
S
F
Rhesus Macaque
Macaca mulatta
XP_001100096
373
40998
S221
T
P
L
K
E
R
I
S
L
P
S
R
R
S
F
Dog
Lupus familis
XP_541735
365
40427
T214
L
V
V
M
L
P
K
T
P
L
K
E
R
I
S
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q791F6
369
40560
S218
T
P
L
K
E
R
V
S
L
P
S
R
R
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001519782
520
56905
E304
G
L
A
F
G
H
L
E
S
K
S
S
I
K
R
Chicken
Gallus gallus
Q5ZII3
364
40350
F217
F
F
F
L
V
Y
S
F
V
V
I
L
P
K
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q4V8X0
378
41685
T227
L
I
V
I
L
P
K
T
P
I
R
E
R
I
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_625021
693
77569
R230
P
W
T
R
L
R
D
R
L
T
L
P
S
K
K
Nematode Worm
Caenorhab. elegans
Q18936
458
51793
K255
V
C
C
Q
K
Y
T
K
L
P
S
K
G
S
F
Sea Urchin
Strong. purpuratus
XP_783628
308
33868
Y161
T
C
V
I
S
L
C
Y
S
V
V
Q
G
C
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
98.6
93.8
N.A.
N.A.
91.4
N.A.
62.3
76.6
N.A.
73.5
N.A.
N.A.
26.2
29.2
34.8
Protein Similarity:
100
99.7
99.1
95.4
N.A.
N.A.
94.9
N.A.
64.2
84.9
N.A.
83.5
N.A.
N.A.
39.9
45.2
49.3
P-Site Identity:
100
100
100
6.6
N.A.
N.A.
93.3
N.A.
6.6
0
N.A.
6.6
N.A.
N.A.
13.3
33.3
6.6
P-Site Similarity:
100
100
100
20
N.A.
N.A.
100
N.A.
13.3
6.6
N.A.
20
N.A.
N.A.
20
53.3
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
19
10
0
0
0
10
0
0
0
0
0
0
10
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
37
0
0
10
0
0
0
19
0
0
0
% E
% Phe:
10
10
10
10
0
0
0
10
0
0
0
0
0
0
46
% F
% Gly:
10
0
0
0
10
0
0
0
0
0
0
0
19
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
19
0
0
28
0
0
10
10
0
10
19
0
% I
% Lys:
0
0
0
37
10
0
19
10
0
10
10
10
0
28
10
% K
% Leu:
19
10
37
10
28
10
10
0
55
10
10
10
0
0
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
37
0
0
0
19
0
0
19
46
0
10
10
0
0
% P
% Gln:
0
0
0
10
0
0
0
0
0
0
0
10
0
0
0
% Q
% Arg:
0
0
0
10
0
46
0
10
0
0
10
37
55
0
10
% R
% Ser:
0
0
0
0
10
0
10
37
19
0
55
10
10
46
19
% S
% Thr:
46
0
10
0
0
0
10
19
0
10
0
0
0
0
10
% T
% Val:
10
10
28
0
10
0
10
0
10
19
10
0
0
0
0
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
19
0
10
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _