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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TPRA1 All Species: 17.58
Human Site: S224 Identified Species: 38.67
UniProt: Q86W33 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86W33 NP_001129525.1 373 41053 S224 K E R I S L P S R R S F Y V Y
Chimpanzee Pan troglodytes XP_001136957 373 41062 S224 K E R I S L P S R R S F Y V Y
Rhesus Macaque Macaca mulatta XP_001100096 373 40998 S224 K E R I S L P S R R S F Y V Y
Dog Lupus familis XP_541735 365 40427 K217 M L P K T P L K E R I S L P S
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus Q791F6 369 40560 S221 K E R V S L P S R R S F Y V Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001519782 520 56905 S307 F G H L E S K S S I K R V L A
Chicken Gallus gallus Q5ZII3 364 40350 I220 L V Y S F V V I L P K T P L K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q4V8X0 378 41685 R230 I L P K T P I R E R I S L P S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_625021 693 77569 L233 R L R D R L T L P S K K S F Y
Nematode Worm Caenorhab. elegans Q18936 458 51793 S258 Q K Y T K L P S K G S F L I Y
Sea Urchin Strong. purpuratus XP_783628 308 33868 V164 I S L C Y S V V Q G C L E V K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.7 98.6 93.8 N.A. N.A. 91.4 N.A. 62.3 76.6 N.A. 73.5 N.A. N.A. 26.2 29.2 34.8
Protein Similarity: 100 99.7 99.1 95.4 N.A. N.A. 94.9 N.A. 64.2 84.9 N.A. 83.5 N.A. N.A. 39.9 45.2 49.3
P-Site Identity: 100 100 100 6.6 N.A. N.A. 93.3 N.A. 6.6 0 N.A. 6.6 N.A. N.A. 20 40 6.6
P-Site Similarity: 100 100 100 13.3 N.A. N.A. 100 N.A. 20 13.3 N.A. 13.3 N.A. N.A. 26.6 66.6 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 10 0 0 0 0 % C
% Asp: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 37 0 0 10 0 0 0 19 0 0 0 10 0 0 % E
% Phe: 10 0 0 0 10 0 0 0 0 0 0 46 0 10 0 % F
% Gly: 0 10 0 0 0 0 0 0 0 19 0 0 0 0 0 % G
% His: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 19 0 0 28 0 0 10 10 0 10 19 0 0 10 0 % I
% Lys: 37 10 0 19 10 0 10 10 10 0 28 10 0 0 19 % K
% Leu: 10 28 10 10 0 55 10 10 10 0 0 10 28 19 0 % L
% Met: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 19 0 0 19 46 0 10 10 0 0 10 19 0 % P
% Gln: 10 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 10 0 46 0 10 0 0 10 37 55 0 10 0 0 0 % R
% Ser: 0 10 0 10 37 19 0 55 10 10 46 19 10 0 19 % S
% Thr: 0 0 0 10 19 0 10 0 0 0 0 10 0 0 0 % T
% Val: 0 10 0 10 0 10 19 10 0 0 0 0 10 46 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 19 0 10 0 0 0 0 0 0 0 37 0 55 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _