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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC6
All Species:
23.03
Human Site:
S249
Identified Species:
46.06
UniProt:
Q86W42
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W42
NP_001135822.1
341
37535
S249
T
L
W
H
L
R
S
S
T
P
T
T
I
F
P
Chimpanzee
Pan troglodytes
XP_001165205
340
37371
S248
T
L
W
H
L
R
S
S
T
P
T
T
I
F
P
Rhesus Macaque
Macaca mulatta
XP_001090442
341
37467
S249
T
L
W
H
L
R
S
S
T
P
T
T
V
F
P
Dog
Lupus familis
XP_536996
328
36150
S236
T
L
W
H
L
R
S
S
T
P
T
T
I
F
P
Cat
Felis silvestris
Mouse
Mus musculus
Q5U4D9
341
37296
S249
T
L
W
H
L
R
S
S
T
P
T
T
V
F
P
Rat
Rattus norvegicus
Q6AY87
341
37404
S249
T
L
W
H
L
R
S
S
T
P
T
T
V
F
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516012
369
40237
A267
T
L
W
H
L
R
S
A
T
P
T
T
V
F
P
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089841
333
37128
M242
S
L
W
H
L
R
S
M
T
P
T
T
I
F
P
Zebra Danio
Brachydanio rerio
Q5XJS5
323
35350
R231
S
L
S
L
W
H
L
R
S
M
S
P
T
S
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTV1
350
39203
M235
S
I
F
H
L
R
S
M
E
S
T
C
V
F
S
Honey Bee
Apis mellifera
XP_001121632
331
37212
T240
L
S
L
W
H
M
R
T
M
E
A
A
T
V
F
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785582
337
36894
L242
P
S
L
S
L
W
H
L
R
S
L
S
P
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
94.1
N.A.
95.3
95.8
N.A.
65
N.A.
59.8
57.4
N.A.
27.7
38.4
N.A.
42.5
Protein Similarity:
100
99.7
99.7
95
N.A.
96.7
97.3
N.A.
72.9
N.A.
75.3
75
N.A.
48
56.2
N.A.
63.6
P-Site Identity:
100
100
93.3
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
86.6
6.6
N.A.
40
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
93.3
26.6
N.A.
66.6
6.6
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
9
0
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% E
% Phe:
0
0
9
0
0
0
0
0
0
0
0
0
0
75
9
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
75
9
9
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
0
0
34
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
75
17
9
84
0
9
9
0
0
9
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
17
9
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
0
0
0
0
67
0
9
9
0
67
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
75
9
9
9
0
0
0
0
0
0
% R
% Ser:
25
17
9
9
0
0
75
50
9
17
9
9
0
9
9
% S
% Thr:
59
0
0
0
0
0
0
9
67
0
75
67
17
9
9
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
42
9
9
% V
% Trp:
0
0
67
9
9
9
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _