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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC6
All Species:
24.55
Human Site:
S297
Identified Species:
49.09
UniProt:
Q86W42
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W42
NP_001135822.1
341
37535
S297
K
A
Q
V
P
G
S
S
P
G
L
L
S
L
S
Chimpanzee
Pan troglodytes
XP_001165205
340
37371
S296
K
A
Q
V
P
G
S
S
P
G
L
L
S
L
S
Rhesus Macaque
Macaca mulatta
XP_001090442
341
37467
S297
K
A
Q
V
P
G
S
S
P
G
L
L
S
L
S
Dog
Lupus familis
XP_536996
328
36150
S284
K
A
Q
V
P
G
S
S
P
G
L
L
S
L
S
Cat
Felis silvestris
Mouse
Mus musculus
Q5U4D9
341
37296
S297
K
A
Q
V
P
G
S
S
P
G
L
L
S
L
S
Rat
Rattus norvegicus
Q6AY87
341
37404
S297
K
A
Q
V
P
G
S
S
P
G
L
L
S
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516012
369
40237
L315
V
S
S
H
H
P
P
L
L
G
D
R
A
E
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089841
333
37128
P290
K
A
Q
I
P
S
T
P
R
C
V
Y
S
L
S
Zebra Danio
Brachydanio rerio
Q5XJS5
323
35350
C279
T
V
K
A
Q
I
P
C
S
P
S
S
L
N
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTV1
350
39203
H283
Q
A
N
I
P
V
E
H
T
A
C
Y
S
A
V
Honey Bee
Apis mellifera
XP_001121632
331
37212
T288
E
M
L
A
K
V
P
T
S
S
N
T
V
Y
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785582
337
36894
T290
N
G
D
S
K
L
T
T
P
C
T
A
M
D
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
94.1
N.A.
95.3
95.8
N.A.
65
N.A.
59.8
57.4
N.A.
27.7
38.4
N.A.
42.5
Protein Similarity:
100
99.7
99.7
95
N.A.
96.7
97.3
N.A.
72.9
N.A.
75.3
75
N.A.
48
56.2
N.A.
63.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
N.A.
46.6
0
N.A.
20
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
20
N.A.
66.6
13.3
N.A.
33.3
20
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
67
0
17
0
0
0
0
0
9
0
9
9
9
0
% A
% Cys:
0
0
0
0
0
0
0
9
0
17
9
0
0
0
0
% C
% Asp:
0
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% D
% Glu:
9
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
9
0
0
0
50
0
0
0
59
0
0
0
0
0
% G
% His:
0
0
0
9
9
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
17
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
59
0
9
0
17
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
9
0
0
9
0
9
9
0
50
50
9
59
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
9
0
9
0
0
0
0
0
0
0
9
0
0
9
0
% N
% Pro:
0
0
0
0
67
9
25
9
59
9
0
0
0
0
0
% P
% Gln:
9
0
59
0
9
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
9
0
0
0
% R
% Ser:
0
9
9
9
0
9
50
50
17
9
9
9
67
0
67
% S
% Thr:
9
0
0
0
0
0
17
17
9
0
9
9
0
0
9
% T
% Val:
9
9
0
50
0
17
0
0
0
0
9
0
9
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
17
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _