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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
THOC6
All Species:
28.48
Human Site:
T168
Identified Species:
56.97
UniProt:
Q86W42
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W42
NP_001135822.1
341
37535
T168
T
R
V
L
R
G
H
T
D
Y
I
H
C
L
A
Chimpanzee
Pan troglodytes
XP_001165205
340
37371
T167
T
R
V
L
R
G
H
T
D
Y
I
H
C
L
A
Rhesus Macaque
Macaca mulatta
XP_001090442
341
37467
T168
T
R
V
L
R
G
H
T
D
Y
I
H
C
L
A
Dog
Lupus familis
XP_536996
328
36150
T155
T
R
A
L
R
G
H
T
D
Y
V
H
C
L
A
Cat
Felis silvestris
Mouse
Mus musculus
Q5U4D9
341
37296
T168
T
R
A
L
R
G
H
T
D
Y
I
H
C
L
A
Rat
Rattus norvegicus
Q6AY87
341
37404
T168
T
R
A
L
R
G
H
T
D
Y
I
H
C
L
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516012
369
40237
S186
T
R
S
L
R
G
H
S
D
Y
I
H
C
L
A
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001089841
333
37128
E161
T
M
T
L
E
G
H
E
D
Y
I
H
C
L
A
Zebra Danio
Brachydanio rerio
Q5XJS5
323
35350
G150
T
F
K
S
V
L
K
G
H
T
D
Y
I
H
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VTV1
350
39203
H154
I
Q
R
E
Y
R
G
H
T
D
Y
V
H
S
V
Honey Bee
Apis mellifera
XP_001121632
331
37212
E159
G
R
I
L
R
S
L
E
G
H
T
D
Y
I
H
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_785582
337
36894
T161
K
H
S
Y
T
D
H
T
D
Y
I
H
A
V
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
99.1
94.1
N.A.
95.3
95.8
N.A.
65
N.A.
59.8
57.4
N.A.
27.7
38.4
N.A.
42.5
Protein Similarity:
100
99.7
99.7
95
N.A.
96.7
97.3
N.A.
72.9
N.A.
75.3
75
N.A.
48
56.2
N.A.
63.6
P-Site Identity:
100
100
100
86.6
N.A.
93.3
93.3
N.A.
86.6
N.A.
73.3
6.6
N.A.
0
20
N.A.
46.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
N.A.
73.3
13.3
N.A.
6.6
40
N.A.
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
0
0
0
0
0
0
9
0
75
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
67
0
9
% C
% Asp:
0
0
0
0
0
9
0
0
75
9
9
9
0
0
0
% D
% Glu:
0
0
0
9
9
0
0
17
0
0
0
0
0
0
0
% E
% Phe:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
0
0
0
0
67
9
9
9
0
0
0
0
0
0
% G
% His:
0
9
0
0
0
0
75
9
9
9
0
75
9
9
9
% H
% Ile:
9
0
9
0
0
0
0
0
0
0
67
0
9
9
0
% I
% Lys:
9
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
75
0
9
9
0
0
0
0
0
0
67
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
9
0
67
9
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
17
9
0
9
0
9
0
0
0
0
0
9
0
% S
% Thr:
75
0
9
0
9
0
0
59
9
9
9
0
0
0
0
% T
% Val:
0
0
25
0
9
0
0
0
0
0
9
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
0
0
0
75
9
9
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _