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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: THOC6 All Species: 21.52
Human Site: T199 Identified Species: 43.03
UniProt: Q86W42 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86W42 NP_001135822.1 341 37535 T199 V R L W D L R T A K E V Q T I
Chimpanzee Pan troglodytes XP_001165205 340 37371 T198 V R L W D L R T A K E V Q T I
Rhesus Macaque Macaca mulatta XP_001090442 341 37467 T199 V R L W D L R T A K E V Q T I
Dog Lupus familis XP_536996 328 36150 T186 V R L W D L R T A K E V Q T I
Cat Felis silvestris
Mouse Mus musculus Q5U4D9 341 37296 I199 V R L W D L R I A K E V Q T I
Rat Rattus norvegicus Q6AY87 341 37404 I199 V R L W D L R I A K E V Q T I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516012 369 40237 T217 V R L W D L R T G E E V Q T I
Chicken Gallus gallus
Frog Xenopus laevis NP_001089841 333 37128 N192 V R I W D L R N G A Q T H K I
Zebra Danio Brachydanio rerio Q5XJS5 323 35350 S181 G A V R I W D S R T N R P V H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VTV1 350 39203 Q185 V R V W S T K Q Q Q H T S M L
Honey Bee Apis mellifera XP_001121632 331 37212 R190 T V R L W D L R K K E N T N I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785582 337 36894 T192 V R I W D T R T S G E P V A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 99.1 94.1 N.A. 95.3 95.8 N.A. 65 N.A. 59.8 57.4 N.A. 27.7 38.4 N.A. 42.5
Protein Similarity: 100 99.7 99.7 95 N.A. 96.7 97.3 N.A. 72.9 N.A. 75.3 75 N.A. 48 56.2 N.A. 63.6
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 N.A. 46.6 0 N.A. 20 20 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 N.A. 60 13.3 N.A. 46.6 20 N.A. 66.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 0 0 0 0 50 9 0 0 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 75 9 9 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 9 75 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 0 0 0 0 0 0 0 17 9 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 9 0 9 0 9 % H
% Ile: 0 0 17 0 9 0 0 17 0 0 0 0 0 0 84 % I
% Lys: 0 0 0 0 0 0 9 0 9 59 0 0 0 9 0 % K
% Leu: 0 0 59 9 0 67 9 0 0 0 0 0 0 0 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 0 9 9 0 9 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % P
% Gln: 0 0 0 0 0 0 0 9 9 9 9 0 59 0 0 % Q
% Arg: 0 84 9 9 0 0 75 9 9 0 0 9 0 0 0 % R
% Ser: 0 0 0 0 9 0 0 9 9 0 0 0 9 0 0 % S
% Thr: 9 0 0 0 0 17 0 50 0 9 0 17 9 59 0 % T
% Val: 84 9 17 0 0 0 0 0 0 0 0 59 9 9 0 % V
% Trp: 0 0 0 84 9 9 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _