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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METT10D
All Species:
31.82
Human Site:
S152
Identified Species:
50
UniProt:
Q86W50
Number Species:
14
Phosphosite Substitution
Charge Score:
0.21
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W50
NP_076991.3
562
63621
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Chimpanzee
Pan troglodytes
XP_523533
562
63576
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Rhesus Macaque
Macaca mulatta
XP_001117412
528
60111
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Dog
Lupus familis
XP_537774
561
63494
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQG2
553
62322
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508494
563
63386
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Chicken
Gallus gallus
Q5ZIA0
558
63368
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Frog
Xenopus laevis
Q6GR37
547
61864
S152
N
V
E
Q
N
N
L
S
D
L
I
K
V
V
K
Zebra Danio
Brachydanio rerio
Q6DC64
471
53602
L126
T
M
N
G
W
F
F
L
A
T
E
V
D
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K3B9
305
35128
Honey Bee
Apis mellifera
XP_624889
356
41810
N11
R
K
F
M
H
P
R
N
K
Y
K
K
I
P
D
Nematode Worm
Caenorhab. elegans
Q09357
479
53786
E134
F
I
A
T
D
G
D
E
K
S
V
R
V
A
H
Sea Urchin
Strong. purpuratus
XP_793611
657
72899
D152
I
T
R
N
G
L
D
D
K
I
T
V
V
E
T
Poplar Tree
Populus trichocarpa
XP_002306173
443
49337
L98
Y
I
H
W
I
E
D
L
L
S
S
D
I
I
P
Maize
Zea mays
NP_001143191
468
50996
D123
S
A
R
V
K
G
F
D
I
G
T
G
A
N
C
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
87.9
92.5
N.A.
87.7
N.A.
N.A.
79
76.3
70.8
65.3
N.A.
22.9
27.7
31.6
35.1
Protein Similarity:
100
99.8
90.5
95
N.A.
91.9
N.A.
N.A.
86.1
84.8
79.1
74.5
N.A.
34.7
43.5
47.1
53.7
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
0
N.A.
0
6.6
6.6
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
100
100
100
6.6
N.A.
0
26.6
33.3
13.3
Percent
Protein Identity:
23.4
25.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.1
40.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
0
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
7
0
0
0
0
0
7
0
0
0
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% C
% Asp:
0
0
0
0
7
0
20
14
54
0
0
7
7
7
7
% D
% Glu:
0
0
54
0
0
7
0
7
0
0
7
0
0
7
0
% E
% Phe:
7
0
7
0
0
7
14
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
7
7
14
0
0
0
7
0
7
0
0
0
% G
% His:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
7
% H
% Ile:
7
14
0
0
7
0
0
0
7
7
54
0
14
7
7
% I
% Lys:
0
7
0
0
7
0
0
0
20
0
7
60
0
0
54
% K
% Leu:
0
0
0
0
0
7
54
14
7
54
0
0
0
0
0
% L
% Met:
0
7
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
54
0
7
7
54
54
0
7
0
0
0
0
0
7
0
% N
% Pro:
0
0
0
0
0
7
0
0
0
0
0
0
0
7
7
% P
% Gln:
0
0
0
54
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
7
0
14
0
0
0
7
0
0
0
0
7
0
0
0
% R
% Ser:
7
0
0
0
0
0
0
54
0
14
7
0
0
0
0
% S
% Thr:
7
7
0
7
0
0
0
0
0
7
14
0
0
0
7
% T
% Val:
0
54
0
7
0
0
0
0
0
0
7
14
67
54
0
% V
% Trp:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
7
0
0
0
0
0
0
0
0
7
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _