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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METT10D All Species: 16.67
Human Site: S329 Identified Species: 26.19
UniProt: Q86W50 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86W50 NP_076991.3 562 63621 S329 K E L S L K A S P L R S E T A
Chimpanzee Pan troglodytes XP_523533 562 63576 S329 K E L S L K A S P L R S E T A
Rhesus Macaque Macaca mulatta XP_001117412 528 60111 S326 K E L S L R A S S L G S E T A
Dog Lupus familis XP_537774 561 63494 S329 K E L S L K A S S L G S E T V
Cat Felis silvestris
Mouse Mus musculus Q9CQG2 553 62322 S329 K E L S L K A S S L G S E T A
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508494 563 63386 L329 K E L A V K A L A L G L D A V
Chicken Gallus gallus Q5ZIA0 558 63368 A329 K E L S I K A A A M G W D A V
Frog Xenopus laevis Q6GR37 547 61864 S329 L L T E K L P S G S E V P E S
Zebra Danio Brachydanio rerio Q6DC64 471 53602 P291 F Y D D V P V P S P P C K K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K3B9 305 35128 K125 I Y S L L G A K K N G W H M L
Honey Bee Apis mellifera XP_624889 356 41810 I176 E E L S E K I I K R L P P R N
Nematode Worm Caenorhab. elegans Q09357 479 53786 L299 G K T K R W M L A W T F S K S
Sea Urchin Strong. purpuratus XP_793611 657 72899 L331 K R V L E P G L S G G L Q N R
Poplar Tree Populus trichocarpa XP_002306173 443 49337 I263 K A F I T C I I E D S V V L K
Maize Zea mays NP_001143191 468 50996 L288 M I G R K A N L K L L I S K V
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 87.9 92.5 N.A. 87.7 N.A. N.A. 79 76.3 70.8 65.3 N.A. 22.9 27.7 31.6 35.1
Protein Similarity: 100 99.8 90.5 95 N.A. 91.9 N.A. N.A. 86.1 84.8 79.1 74.5 N.A. 34.7 43.5 47.1 53.7
P-Site Identity: 100 100 80 80 N.A. 86.6 N.A. N.A. 40 40 6.6 0 N.A. 13.3 26.6 0 6.6
P-Site Similarity: 100 100 86.6 80 N.A. 86.6 N.A. N.A. 60 66.6 13.3 13.3 N.A. 13.3 33.3 13.3 20
Percent
Protein Identity: 23.4 25.4 N.A. N.A. N.A. N.A.
Protein Similarity: 39.1 40.5 N.A. N.A. N.A. N.A.
P-Site Identity: 6.6 6.6 N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 6.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 7 0 7 54 7 20 0 0 0 0 14 27 % A
% Cys: 0 0 0 0 0 7 0 0 0 0 0 7 0 0 0 % C
% Asp: 0 0 7 7 0 0 0 0 0 7 0 0 14 0 0 % D
% Glu: 7 54 0 7 14 0 0 0 7 0 7 0 34 7 0 % E
% Phe: 7 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 7 0 7 0 0 7 7 0 7 7 47 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % H
% Ile: 7 7 0 7 7 0 14 14 0 0 0 7 0 0 0 % I
% Lys: 60 7 0 7 14 47 0 7 20 0 0 0 7 20 7 % K
% Leu: 7 7 54 14 40 7 0 27 0 47 14 14 0 7 7 % L
% Met: 7 0 0 0 0 0 7 0 0 7 0 0 0 7 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 7 0 0 0 7 7 % N
% Pro: 0 0 0 0 0 14 7 7 14 7 7 7 14 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Q
% Arg: 0 7 0 7 7 7 0 0 0 7 14 0 0 7 14 % R
% Ser: 0 0 7 47 0 0 0 40 34 7 7 34 14 0 14 % S
% Thr: 0 0 14 0 7 0 0 0 0 0 7 0 0 34 0 % T
% Val: 0 0 7 0 14 0 7 0 0 0 0 14 7 0 27 % V
% Trp: 0 0 0 0 0 7 0 0 0 7 0 14 0 0 0 % W
% Tyr: 0 14 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _