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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METT10D
All Species:
16.06
Human Site:
S333
Identified Species:
25.24
UniProt:
Q86W50
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W50
NP_076991.3
562
63621
S333
L
K
A
S
P
L
R
S
E
T
A
E
G
I
V
Chimpanzee
Pan troglodytes
XP_523533
562
63576
S333
L
K
A
S
P
L
R
S
E
T
A
E
G
I
V
Rhesus Macaque
Macaca mulatta
XP_001117412
528
60111
S330
L
R
A
S
S
L
G
S
E
T
A
E
G
I
V
Dog
Lupus familis
XP_537774
561
63494
S333
L
K
A
S
S
L
G
S
E
T
V
E
G
I
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQG2
553
62322
S333
L
K
A
S
S
L
G
S
E
T
A
E
G
I
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508494
563
63386
L333
V
K
A
L
A
L
G
L
D
A
V
G
G
I
A
Chicken
Gallus gallus
Q5ZIA0
558
63368
W333
I
K
A
A
A
M
G
W
D
A
V
E
G
I
A
Frog
Xenopus laevis
Q6GR37
547
61864
V333
K
L
P
S
G
S
E
V
P
E
S
I
T
L
V
Zebra Danio
Brachydanio rerio
Q6DC64
471
53602
C295
V
P
V
P
S
P
P
C
K
K
R
K
L
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K3B9
305
35128
W129
L
G
A
K
K
N
G
W
H
M
L
A
L
E
S
Honey Bee
Apis mellifera
XP_624889
356
41810
P180
E
K
I
I
K
R
L
P
P
R
N
A
S
T
G
Nematode Worm
Caenorhab. elegans
Q09357
479
53786
F303
R
W
M
L
A
W
T
F
S
K
S
V
S
L
T
Sea Urchin
Strong. purpuratus
XP_793611
657
72899
L335
E
P
G
L
S
G
G
L
Q
N
R
I
Q
S
V
Poplar Tree
Populus trichocarpa
XP_002306173
443
49337
V267
T
C
I
I
E
D
S
V
V
L
K
E
S
F
R
Maize
Zea mays
NP_001143191
468
50996
I292
K
A
N
L
K
L
L
I
S
K
V
R
E
A
G
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
87.9
92.5
N.A.
87.7
N.A.
N.A.
79
76.3
70.8
65.3
N.A.
22.9
27.7
31.6
35.1
Protein Similarity:
100
99.8
90.5
95
N.A.
91.9
N.A.
N.A.
86.1
84.8
79.1
74.5
N.A.
34.7
43.5
47.1
53.7
P-Site Identity:
100
100
80
80
N.A.
86.6
N.A.
N.A.
33.3
33.3
13.3
0
N.A.
13.3
6.6
0
6.6
P-Site Similarity:
100
100
86.6
80
N.A.
86.6
N.A.
N.A.
46.6
60
26.6
20
N.A.
13.3
6.6
13.3
13.3
Percent
Protein Identity:
23.4
25.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.1
40.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
54
7
20
0
0
0
0
14
27
14
0
7
14
% A
% Cys:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
7
0
0
14
0
0
0
0
0
0
% D
% Glu:
14
0
0
0
7
0
7
0
34
7
0
47
7
14
0
% E
% Phe:
0
0
0
0
0
0
0
7
0
0
0
0
0
7
0
% F
% Gly:
0
7
7
0
7
7
47
0
0
0
0
7
47
0
14
% G
% His:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% H
% Ile:
7
0
14
14
0
0
0
7
0
0
0
14
0
47
0
% I
% Lys:
14
47
0
7
20
0
0
0
7
20
7
7
0
0
7
% K
% Leu:
40
7
0
27
0
47
14
14
0
7
7
0
14
14
0
% L
% Met:
0
0
7
0
0
7
0
0
0
7
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
0
0
7
7
0
0
0
0
% N
% Pro:
0
14
7
7
14
7
7
7
14
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
7
0
0
0
7
0
0
% Q
% Arg:
7
7
0
0
0
7
14
0
0
7
14
7
0
0
7
% R
% Ser:
0
0
0
40
34
7
7
34
14
0
14
0
20
7
7
% S
% Thr:
7
0
0
0
0
0
7
0
0
34
0
0
7
7
7
% T
% Val:
14
0
7
0
0
0
0
14
7
0
27
7
0
0
47
% V
% Trp:
0
7
0
0
0
7
0
14
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _