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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METT10D
All Species:
12.42
Human Site:
S455
Identified Species:
19.52
UniProt:
Q86W50
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W50
NP_076991.3
562
63621
S455
C
P
S
Q
E
S
L
S
Q
E
E
N
P
E
P
Chimpanzee
Pan troglodytes
XP_523533
562
63576
S455
C
P
S
Q
E
S
L
S
Q
E
E
N
P
E
P
Rhesus Macaque
Macaca mulatta
XP_001117412
528
60111
C447
A
V
E
G
P
C
L
C
Q
E
S
L
S
Q
E
Dog
Lupus familis
XP_537774
561
63494
S455
C
S
S
Q
D
L
L
S
Q
E
E
N
P
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQG2
553
62322
C455
C
L
S
Q
K
L
L
C
Q
E
E
T
P
E
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508494
563
63386
P456
S
P
E
D
K
D
S
P
A
Q
E
I
S
E
K
Chicken
Gallus gallus
Q5ZIA0
558
63368
P437
S
E
T
E
L
V
A
P
D
E
D
V
H
L
T
Frog
Xenopus laevis
Q6GR37
547
61864
N461
S
E
P
M
E
A
E
N
S
D
S
K
P
D
E
Zebra Danio
Brachydanio rerio
Q6DC64
471
53602
E390
R
E
L
P
R
A
Q
E
P
P
S
E
E
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K3B9
305
35128
L224
R
T
G
S
Q
E
E
L
T
C
V
G
G
E
V
Honey Bee
Apis mellifera
XP_624889
356
41810
P275
F
V
N
L
I
N
A
P
V
I
R
K
S
E
D
Nematode Worm
Caenorhab. elegans
Q09357
479
53786
S398
G
A
G
D
G
K
D
S
Y
T
D
A
G
N
F
Sea Urchin
Strong. purpuratus
XP_793611
657
72899
T513
D
P
S
T
S
T
A
T
R
S
E
K
L
P
T
Poplar Tree
Populus trichocarpa
XP_002306173
443
49337
F362
L
Q
S
I
E
S
F
F
C
L
G
G
A
S
C
Maize
Zea mays
NP_001143191
468
50996
S387
F
S
V
D
V
T
L
S
D
E
Q
I
E
A
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
87.9
92.5
N.A.
87.7
N.A.
N.A.
79
76.3
70.8
65.3
N.A.
22.9
27.7
31.6
35.1
Protein Similarity:
100
99.8
90.5
95
N.A.
91.9
N.A.
N.A.
86.1
84.8
79.1
74.5
N.A.
34.7
43.5
47.1
53.7
P-Site Identity:
100
100
20
80
N.A.
60
N.A.
N.A.
20
6.6
13.3
0
N.A.
6.6
6.6
6.6
20
P-Site Similarity:
100
100
26.6
86.6
N.A.
66.6
N.A.
N.A.
33.3
26.6
40
6.6
N.A.
13.3
20
13.3
40
Percent
Protein Identity:
23.4
25.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.1
40.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
20
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
14
20
0
7
0
0
7
7
7
14
% A
% Cys:
27
0
0
0
0
7
0
14
7
7
0
0
0
0
7
% C
% Asp:
7
0
0
20
7
7
7
0
14
7
14
0
0
7
7
% D
% Glu:
0
20
14
7
27
7
14
7
0
47
40
7
14
47
14
% E
% Phe:
14
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% F
% Gly:
7
0
14
7
7
0
0
0
0
0
7
14
14
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% H
% Ile:
0
0
0
7
7
0
0
0
0
7
0
14
0
0
0
% I
% Lys:
0
0
0
0
14
7
0
0
0
0
0
20
0
0
7
% K
% Leu:
7
7
7
7
7
14
40
7
0
7
0
7
7
7
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
7
0
7
0
0
0
20
0
7
0
% N
% Pro:
0
27
7
7
7
0
0
20
7
7
0
0
34
7
20
% P
% Gln:
0
7
0
27
7
0
7
0
34
7
7
0
0
7
0
% Q
% Arg:
14
0
0
0
7
0
0
0
7
0
7
0
0
0
0
% R
% Ser:
20
14
40
7
7
20
7
34
7
7
20
0
20
7
7
% S
% Thr:
0
7
7
7
0
14
0
7
7
7
0
7
0
7
14
% T
% Val:
0
14
7
0
7
7
0
0
7
0
7
7
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _