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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METT10D
All Species:
18.48
Human Site:
T294
Identified Species:
29.05
UniProt:
Q86W50
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W50
NP_076991.3
562
63621
T294
W
S
F
Y
D
D
V
T
V
P
S
P
P
S
K
Chimpanzee
Pan troglodytes
XP_523533
562
63576
T294
W
S
F
Y
D
D
V
T
V
P
S
P
P
S
K
Rhesus Macaque
Macaca mulatta
XP_001117412
528
60111
V291
W
T
W
W
H
S
P
V
I
P
S
P
P
S
K
Dog
Lupus familis
XP_537774
561
63494
T294
W
S
F
Y
D
D
V
T
V
P
S
P
P
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQG2
553
62322
T294
W
S
F
Y
D
D
V
T
V
P
S
P
P
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508494
563
63386
T294
W
S
F
Y
D
D
V
T
V
P
S
P
P
S
K
Chicken
Gallus gallus
Q5ZIA0
558
63368
Q294
W
S
F
Y
D
D
V
Q
V
P
S
P
P
S
K
Frog
Xenopus laevis
Q6GR37
547
61864
I294
W
S
F
Y
E
E
V
I
I
P
N
P
P
K
K
Zebra Danio
Brachydanio rerio
Q6DC64
471
53602
E256
S
L
A
P
L
K
D
E
L
R
K
Q
G
V
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K3B9
305
35128
Y90
T
L
A
L
R
L
N
Y
I
L
W
L
E
D
L
Honey Bee
Apis mellifera
XP_624889
356
41810
N141
D
E
T
I
F
K
V
N
E
G
T
I
L
K
G
Nematode Worm
Caenorhab. elegans
Q09357
479
53786
R264
I
Y
T
T
M
I
G
R
K
S
S
L
K
P
L
Sea Urchin
Strong. purpuratus
XP_793611
657
72899
E296
W
T
F
K
E
D
M
E
S
P
L
L
A
C
P
Poplar Tree
Populus trichocarpa
XP_002306173
443
49337
F228
C
M
C
N
P
P
F
F
E
T
M
E
E
A
G
Maize
Zea mays
NP_001143191
468
50996
C253
G
T
A
E
E
M
V
C
P
G
G
E
L
A
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
87.9
92.5
N.A.
87.7
N.A.
N.A.
79
76.3
70.8
65.3
N.A.
22.9
27.7
31.6
35.1
Protein Similarity:
100
99.8
90.5
95
N.A.
91.9
N.A.
N.A.
86.1
84.8
79.1
74.5
N.A.
34.7
43.5
47.1
53.7
P-Site Identity:
100
100
46.6
100
N.A.
100
N.A.
N.A.
100
93.3
60
0
N.A.
0
6.6
6.6
26.6
P-Site Similarity:
100
100
73.3
100
N.A.
100
N.A.
N.A.
100
93.3
86.6
6.6
N.A.
6.6
13.3
6.6
46.6
Percent
Protein Identity:
23.4
25.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.1
40.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
6.6
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
20
0
0
0
0
0
0
0
0
0
7
14
7
% A
% Cys:
7
0
7
0
0
0
0
7
0
0
0
0
0
7
0
% C
% Asp:
7
0
0
0
40
47
7
0
0
0
0
0
0
7
0
% D
% Glu:
0
7
0
7
20
7
0
14
14
0
0
14
14
0
0
% E
% Phe:
0
0
54
0
7
0
7
7
0
0
0
0
0
0
7
% F
% Gly:
7
0
0
0
0
0
7
0
0
14
7
0
7
0
14
% G
% His:
0
0
0
0
7
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
0
7
0
7
20
0
0
7
0
0
0
% I
% Lys:
0
0
0
7
0
14
0
0
7
0
7
0
7
14
54
% K
% Leu:
0
14
0
7
7
7
0
0
7
7
7
20
14
0
14
% L
% Met:
0
7
0
0
7
7
7
0
0
0
7
0
0
0
0
% M
% Asn:
0
0
0
7
0
0
7
7
0
0
7
0
0
0
0
% N
% Pro:
0
0
0
7
7
7
7
0
7
60
0
54
54
7
7
% P
% Gln:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% Q
% Arg:
0
0
0
0
7
0
0
7
0
7
0
0
0
0
0
% R
% Ser:
7
47
0
0
0
7
0
0
7
7
54
0
0
47
0
% S
% Thr:
7
20
14
7
0
0
0
34
0
7
7
0
0
0
0
% T
% Val:
0
0
0
0
0
0
60
7
40
0
0
0
0
7
0
% V
% Trp:
60
0
7
7
0
0
0
0
0
0
7
0
0
0
0
% W
% Tyr:
0
7
0
47
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _