Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: METT10D All Species: 18.18
Human Site: T412 Identified Species: 28.57
UniProt: Q86W50 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86W50 NP_076991.3 562 63621 T412 A L E E K K P T P K E S G N S
Chimpanzee Pan troglodytes XP_523533 562 63576 T412 A L E E K K A T P K E S G N S
Rhesus Macaque Macaca mulatta XP_001117412 528 60111 T409 A L E E K K S T P K E S G N S
Dog Lupus familis XP_537774 561 63494 T412 A L E E K K S T P K E S G S S
Cat Felis silvestris
Mouse Mus musculus Q9CQG2 553 62322 T412 A L E E R K S T P K E L S S G
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508494 563 63386 L412 A M G E G R N L P K E A E S C
Chicken Gallus gallus Q5ZIA0 558 63368 L392 K R E R V R Q L R E L P R A S
Frog Xenopus laevis Q6GR37 547 61864 D415 A L H K E T S D Q G Q N S G D
Zebra Danio Brachydanio rerio Q6DC64 471 53602 G352 V L H K R V P G G E V E L S L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7K3B9 305 35128 L186 Q L Q Y Q F C L C N P P F F D
Honey Bee Apis mellifera XP_624889 356 41810 K237 L F L L K F L K Q K N I E N V
Nematode Worm Caenorhab. elegans Q09357 479 53786 R360 C V T W T N Q R A R K R A K A
Sea Urchin Strong. purpuratus XP_793611 657 72899 S448 S R K D T F P S S S A S S S F
Poplar Tree Populus trichocarpa XP_002306173 443 49337 V324 A W S F V P P V R K I I S P L
Maize Zea mays NP_001143191 468 50996 L349 H S F M L Q G L R R E H G A F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 87.9 92.5 N.A. 87.7 N.A. N.A. 79 76.3 70.8 65.3 N.A. 22.9 27.7 31.6 35.1
Protein Similarity: 100 99.8 90.5 95 N.A. 91.9 N.A. N.A. 86.1 84.8 79.1 74.5 N.A. 34.7 43.5 47.1 53.7
P-Site Identity: 100 93.3 93.3 86.6 N.A. 60 N.A. N.A. 33.3 13.3 13.3 13.3 N.A. 6.6 20 0 13.3
P-Site Similarity: 100 93.3 93.3 93.3 N.A. 73.3 N.A. N.A. 60 26.6 40 40 N.A. 20 20 26.6 46.6
Percent
Protein Identity: 23.4 25.4 N.A. N.A. N.A. N.A.
Protein Similarity: 39.1 40.5 N.A. N.A. N.A. N.A.
P-Site Identity: 20 13.3 N.A. N.A. N.A. N.A.
P-Site Similarity: 20 26.6 N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 54 0 0 0 0 0 7 0 7 0 7 7 7 14 7 % A
% Cys: 7 0 0 0 0 0 7 0 7 0 0 0 0 0 7 % C
% Asp: 0 0 0 7 0 0 0 7 0 0 0 0 0 0 14 % D
% Glu: 0 0 40 40 7 0 0 0 0 14 47 7 14 0 0 % E
% Phe: 0 7 7 7 0 20 0 0 0 0 0 0 7 7 14 % F
% Gly: 0 0 7 0 7 0 7 7 7 7 0 0 34 7 7 % G
% His: 7 0 14 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 14 0 0 0 % I
% Lys: 7 0 7 14 34 34 0 7 0 54 7 0 0 7 0 % K
% Leu: 7 54 7 7 7 0 7 27 0 0 7 7 7 0 14 % L
% Met: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 7 0 0 7 7 7 0 27 0 % N
% Pro: 0 0 0 0 0 7 27 0 40 0 7 14 0 7 0 % P
% Gln: 7 0 7 0 7 7 14 0 14 0 7 0 0 0 0 % Q
% Arg: 0 14 0 7 14 14 0 7 20 14 0 7 7 0 0 % R
% Ser: 7 7 7 0 0 0 27 7 7 7 0 34 27 34 34 % S
% Thr: 0 0 7 0 14 7 0 34 0 0 0 0 0 0 0 % T
% Val: 7 7 0 0 14 7 0 7 0 0 7 0 0 0 7 % V
% Trp: 0 7 0 7 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _