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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METT10D
All Species:
32.12
Human Site:
Y245
Identified Species:
50.48
UniProt:
Q86W50
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W50
NP_076991.3
562
63621
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Chimpanzee
Pan troglodytes
XP_523533
562
63576
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Rhesus Macaque
Macaca mulatta
XP_001117412
528
60111
W244
Q
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
Dog
Lupus familis
XP_537774
561
63494
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9CQG2
553
62322
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508494
563
63386
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Chicken
Gallus gallus
Q5ZIA0
558
63368
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Frog
Xenopus laevis
Q6GR37
547
61864
Y245
L
K
K
R
L
R
W
Y
S
C
M
L
G
K
K
Zebra Danio
Brachydanio rerio
Q6DC64
471
53602
G209
P
S
S
I
N
T
G
G
V
T
E
I
M
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7K3B9
305
35128
L43
R
Q
Q
C
Q
L
E
L
N
G
K
V
S
V
N
Honey Bee
Apis mellifera
XP_624889
356
41810
Y94
W
I
E
D
L
M
K
Y
I
S
F
N
E
M
Q
Nematode Worm
Caenorhab. elegans
Q09357
479
53786
R217
N
R
V
A
S
E
F
R
T
A
P
H
S
A
T
Sea Urchin
Strong. purpuratus
XP_793611
657
72899
Y247
L
R
N
Q
V
V
W
Y
T
S
M
L
G
K
K
Poplar Tree
Populus trichocarpa
XP_002306173
443
49337
E181
C
Q
S
A
I
S
I
E
D
S
N
C
G
E
S
Maize
Zea mays
NP_001143191
468
50996
K206
A
E
D
V
A
M
P
K
P
H
I
L
V
G
V
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
87.9
92.5
N.A.
87.7
N.A.
N.A.
79
76.3
70.8
65.3
N.A.
22.9
27.7
31.6
35.1
Protein Similarity:
100
99.8
90.5
95
N.A.
91.9
N.A.
N.A.
86.1
84.8
79.1
74.5
N.A.
34.7
43.5
47.1
53.7
P-Site Identity:
100
100
13.3
100
N.A.
100
N.A.
N.A.
100
100
100
0
N.A.
0
13.3
0
53.3
P-Site Similarity:
100
100
33.3
100
N.A.
100
N.A.
N.A.
100
100
100
13.3
N.A.
26.6
26.6
20
80
Percent
Protein Identity:
23.4
25.4
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
39.1
40.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
20
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
0
14
7
0
0
0
0
7
0
0
0
14
0
% A
% Cys:
7
0
0
7
0
0
0
0
0
47
7
7
0
0
0
% C
% Asp:
0
0
7
7
0
0
0
0
7
0
0
0
0
0
0
% D
% Glu:
0
7
7
0
0
7
7
7
0
0
7
0
7
7
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
7
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
7
7
0
7
0
0
60
14
0
% G
% His:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% H
% Ile:
0
7
0
7
7
0
7
0
7
0
7
7
0
0
0
% I
% Lys:
0
47
54
7
0
0
7
7
0
0
7
0
0
54
60
% K
% Leu:
54
7
0
0
54
14
0
7
0
0
0
60
7
0
0
% L
% Met:
0
0
0
0
0
14
0
0
0
0
54
7
7
7
0
% M
% Asn:
7
0
7
0
7
0
0
0
7
0
7
7
0
0
7
% N
% Pro:
7
0
0
0
0
0
7
0
7
0
7
0
0
0
0
% P
% Gln:
7
14
7
7
7
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
7
14
0
47
7
47
7
7
0
0
0
0
0
0
0
% R
% Ser:
0
7
14
0
7
7
0
0
47
27
0
0
14
0
7
% S
% Thr:
0
0
0
0
0
7
0
0
14
7
0
0
0
0
7
% T
% Val:
0
0
7
7
7
7
0
0
7
0
0
7
7
7
7
% V
% Trp:
7
0
0
0
0
0
54
7
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
7
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _