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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ANKRD46
All Species:
6.17
Human Site:
S227
Identified Species:
19.39
UniProt:
Q86W74
Number Species:
7
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86W74
NP_940683.1
232
25967
S227
S
F
A
R
Q
D
R
S
R
I
Q
A
I
_
_
Chimpanzee
Pan troglodytes
XP_001152764
232
25948
S227
S
F
A
R
Q
D
R
S
R
I
Q
A
I
_
_
Rhesus Macaque
Macaca mulatta
XP_001097451
227
25435
Dog
Lupus familis
XP_532285
228
25281
Cat
Felis silvestris
Mouse
Mus musculus
Q8BTZ5
228
25204
Rat
Rattus norvegicus
Q76K24
228
25162
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515128
228
25247
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6TNT2
228
25102
S222
G
V
L
P
F
S
A
S
Q
L
E
L
V
H
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
97.4
91.8
N.A.
90.5
90.9
N.A.
90.5
N.A.
N.A.
81.9
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
100
97.4
92.6
N.A.
91.3
91.8
N.A.
91.3
N.A.
N.A.
87.9
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
0
0
N.A.
0
0
N.A.
0
N.A.
N.A.
7.1
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
0
0
N.A.
0
0
N.A.
0
N.A.
N.A.
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
25
0
0
0
13
0
0
0
0
25
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
25
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
13
0
0
0
0
% E
% Phe:
0
25
0
0
13
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
25
0
0
25
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
13
0
0
0
0
0
0
13
0
13
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
25
0
0
0
13
0
25
0
0
0
0
% Q
% Arg:
0
0
0
25
0
0
25
0
25
0
0
0
0
0
0
% R
% Ser:
25
0
0
0
0
13
0
38
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
25
38
% _