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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP2 All Species: 18.79
Human Site: S281 Identified Species: 29.52
UniProt: Q86WA8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WA8 NP_113678.2 852 94617 S281 E K K I R T S S M P E Q A H K
Chimpanzee Pan troglodytes XP_520624 708 78938 R241 P K Q D D D K R V I A I R P I
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535313 852 94548 S281 E R K I R T S S M P E Q A H K
Cat Felis silvestris
Mouse Mus musculus Q9DBN5 852 94508 S281 E K K I R T S S M P E Q A H K
Rat Rattus norvegicus Q3MIB4 852 94375 S281 E K K I R T S S M P E Q A H K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507605 803 89473 Y263 E Y A L T R N Y L E L M V E L
Chicken Gallus gallus XP_414106 852 94661 S281 E K K I R T S S M S E Q A L K
Frog Xenopus laevis Q2TAF8 856 94553 N285 E R K I K S S N M P E P A L K
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 A281 E R K V K A A A M P E A A L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44952 971 108188 A418 D E R I K T L A V P E Y A L K
Sea Urchin Strong. purpuratus XP_001184272 542 60315 L75 N H R M P H A L K E D K E N R
Poplar Tree Populus trichocarpa XP_002329591 893 98616 G319 E R K M Q S A G M P S N I W K
Maize Zea mays P93647 885 97714 G314 E R K M Q N A G M P A N I W K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64948 888 97843 G313 E R K M Q A A G M P S N I W K
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 K538 K E R I K S L K L P D S V Q K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.2 N.A. 97.4 N.A. 95.5 95.1 N.A. 84.8 91.1 83.4 78.6 N.A. N.A. N.A. 31.3 38.6
Protein Similarity: 100 81.6 N.A. 98.2 N.A. 97.7 97.7 N.A. 88 94.9 91.8 87.9 N.A. N.A. N.A. 51.1 49.6
P-Site Identity: 100 6.6 N.A. 93.3 N.A. 100 100 N.A. 6.6 86.6 60 40 N.A. N.A. N.A. 40 0
P-Site Similarity: 100 20 N.A. 100 N.A. 100 100 N.A. 26.6 86.6 86.6 80 N.A. N.A. N.A. 80 46.6
Percent
Protein Identity: 43.9 45.7 N.A. 44.3 29.5 N.A.
Protein Similarity: 62.3 64.7 N.A. 63.2 47.5 N.A.
P-Site Identity: 33.3 33.3 N.A. 33.3 20 N.A.
P-Site Similarity: 66.6 60 N.A. 60 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 0 0 14 34 14 0 0 14 7 54 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 0 7 7 7 0 0 0 0 14 0 0 0 0 % D
% Glu: 74 14 0 0 0 0 0 0 0 14 54 0 7 7 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 20 0 0 0 0 0 0 0 % G
% His: 0 7 0 0 0 7 0 0 0 0 0 0 0 27 0 % H
% Ile: 0 0 0 54 0 0 0 0 0 7 0 7 20 0 7 % I
% Lys: 7 34 67 0 27 0 7 7 7 0 0 7 0 0 74 % K
% Leu: 0 0 0 7 0 0 14 7 14 0 7 0 0 27 7 % L
% Met: 0 0 0 27 0 0 0 0 67 0 0 7 0 0 0 % M
% Asn: 7 0 0 0 0 7 7 7 0 0 0 20 0 7 0 % N
% Pro: 7 0 0 0 7 0 0 0 0 74 0 7 0 7 0 % P
% Gln: 0 0 7 0 20 0 0 0 0 0 0 34 0 7 0 % Q
% Arg: 0 40 20 0 34 7 0 7 0 0 0 0 7 0 14 % R
% Ser: 0 0 0 0 0 20 40 34 0 7 14 7 0 0 0 % S
% Thr: 0 0 0 0 7 40 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 7 0 0 0 0 14 0 0 0 14 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 0 % W
% Tyr: 0 7 0 0 0 0 0 7 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _