Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP2 All Species: 21.52
Human Site: S592 Identified Species: 33.81
UniProt: Q86WA8 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WA8 NP_113678.2 852 94617 S592 K E A K L D R S D V T E R E G
Chimpanzee Pan troglodytes XP_520624 708 78938 A495 I A T A N T T A T I P A A L L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535313 852 94548 Y592 K E A K L D R Y D V A E G E G
Cat Felis silvestris
Mouse Mus musculus Q9DBN5 852 94508 S592 K E A K L D R S D V A D G E G
Rat Rattus norvegicus Q3MIB4 852 94375 S592 K E A K L D R S D V A D G E G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507605 803 89473 S542 E E A E A Q R S E M I A Q G E
Chicken Gallus gallus XP_414106 852 94661 S592 K E T K P D R S E L G E G E D
Frog Xenopus laevis Q2TAF8 856 94553 L596 R E H K S E H L E A P E G E E
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 Q583 A V K V A E G Q K V S R S E A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44952 971 108188 A718 R K A A L Q I A E Q Q N E D E
Sea Urchin Strong. purpuratus XP_001184272 542 60315 F329 F D L S Q V L F I A T A N S L
Poplar Tree Populus trichocarpa XP_002329591 893 98616 A624 R V A E Q E Q A V P L S K D M
Maize Zea mays P93647 885 97714 T619 K V A E Q V K T L R L G K E I
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64948 888 97843 S618 M V A E H E Q S L P L S K D V
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 K870 E K A E N N A K S S S E K T K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.2 N.A. 97.4 N.A. 95.5 95.1 N.A. 84.8 91.1 83.4 78.6 N.A. N.A. N.A. 31.3 38.6
Protein Similarity: 100 81.6 N.A. 98.2 N.A. 97.7 97.7 N.A. 88 94.9 91.8 87.9 N.A. N.A. N.A. 51.1 49.6
P-Site Identity: 100 0 N.A. 80 N.A. 80 80 N.A. 26.6 53.3 26.6 13.3 N.A. N.A. N.A. 13.3 6.6
P-Site Similarity: 100 13.3 N.A. 80 N.A. 86.6 86.6 N.A. 60 66.6 46.6 26.6 N.A. N.A. N.A. 46.6 13.3
Percent
Protein Identity: 43.9 45.7 N.A. 44.3 29.5 N.A.
Protein Similarity: 62.3 64.7 N.A. 63.2 47.5 N.A.
P-Site Identity: 6.6 20 N.A. 13.3 13.3 N.A.
P-Site Similarity: 53.3 46.6 N.A. 46.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 67 14 14 0 7 20 0 14 20 20 7 0 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 0 0 0 34 0 0 27 0 0 14 0 20 7 % D
% Glu: 14 47 0 34 0 27 0 0 27 0 0 34 7 54 20 % E
% Phe: 7 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 7 0 0 0 7 7 34 7 27 % G
% His: 0 0 7 0 7 0 7 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 0 0 0 0 7 0 7 7 7 0 0 0 7 % I
% Lys: 40 14 7 40 0 0 7 7 7 0 0 0 27 0 7 % K
% Leu: 0 0 7 0 34 0 7 7 14 7 20 0 0 7 14 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 0 0 7 % M
% Asn: 0 0 0 0 14 7 0 0 0 0 0 7 7 0 0 % N
% Pro: 0 0 0 0 7 0 0 0 0 14 14 0 0 0 0 % P
% Gln: 0 0 0 0 20 14 14 7 0 7 7 0 7 0 0 % Q
% Arg: 20 0 0 0 0 0 40 0 0 7 0 7 7 0 0 % R
% Ser: 0 0 0 7 7 0 0 40 7 7 14 14 7 7 0 % S
% Thr: 0 0 14 0 0 7 7 7 7 0 14 0 0 7 0 % T
% Val: 0 27 0 7 0 14 0 0 7 34 0 0 0 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _