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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: LONP2 All Species: 50
Human Site: Y417 Identified Species: 78.57
UniProt: Q86WA8 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WA8 NP_113678.2 852 94617 Y417 I R G H R R T Y V G S M P G R
Chimpanzee Pan troglodytes XP_520624 708 78938 E355 K L K K R V L E Y L A V R Q L
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535313 852 94548 Y417 I R G H R R T Y V G S M P G R
Cat Felis silvestris
Mouse Mus musculus Q9DBN5 852 94508 Y417 I R G H R R T Y V G S M P G R
Rat Rattus norvegicus Q3MIB4 852 94375 Y417 I R G H R R T Y V G S M P G R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507605 803 89473 G378 M P G R I I N G L K T V G V N
Chicken Gallus gallus XP_414106 852 94661 Y417 I R G H R R T Y V G S M P G R
Frog Xenopus laevis Q2TAF8 856 94553 Y421 I R G H R R T Y V G S M P G R
Zebra Danio Brachydanio rerio Q5PQY6 840 92202 Y417 I R G H R R T Y V G S M P G R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O44952 971 108188 Y554 I K G H R R T Y V G A M P G K
Sea Urchin Strong. purpuratus XP_001184272 542 60315 D189 D A D H Y G L D K L K K R V I
Poplar Tree Populus trichocarpa XP_002329591 893 98616 Y456 I R G H R R T Y I G S M P G R
Maize Zea mays P93647 885 97714 Y451 I R G H R R T Y I G S M P G R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O64948 888 97843 Y450 I R G H R R T Y I G S M P G R
Baker's Yeast Sacchar. cerevisiae P36775 1133 127093 Y674 I K G H R R T Y I G A L P G R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 80.2 N.A. 97.4 N.A. 95.5 95.1 N.A. 84.8 91.1 83.4 78.6 N.A. N.A. N.A. 31.3 38.6
Protein Similarity: 100 81.6 N.A. 98.2 N.A. 97.7 97.7 N.A. 88 94.9 91.8 87.9 N.A. N.A. N.A. 51.1 49.6
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 100 N.A. 6.6 100 100 100 N.A. N.A. N.A. 80 6.6
P-Site Similarity: 100 20 N.A. 100 N.A. 100 100 N.A. 33.3 100 100 100 N.A. N.A. N.A. 100 6.6
Percent
Protein Identity: 43.9 45.7 N.A. 44.3 29.5 N.A.
Protein Similarity: 62.3 64.7 N.A. 63.2 47.5 N.A.
P-Site Identity: 93.3 93.3 N.A. 93.3 73.3 N.A.
P-Site Similarity: 100 100 N.A. 100 100 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 7 0 0 0 0 0 0 0 0 20 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 0 7 0 0 0 0 7 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 87 0 0 7 0 7 0 80 0 0 7 80 0 % G
% His: 0 0 0 87 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 80 0 0 0 7 7 0 0 27 0 0 0 0 0 7 % I
% Lys: 7 14 7 7 0 0 0 0 7 7 7 7 0 0 7 % K
% Leu: 0 7 0 0 0 0 14 0 7 14 0 7 0 0 7 % L
% Met: 7 0 0 0 0 0 0 0 0 0 0 74 0 0 0 % M
% Asn: 0 0 0 0 0 0 7 0 0 0 0 0 0 0 7 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 0 0 80 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 67 0 7 87 80 0 0 0 0 0 0 14 0 74 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 80 0 0 0 7 0 0 0 0 % T
% Val: 0 0 0 0 0 7 0 0 54 0 0 14 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 0 0 80 7 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _