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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3HC1
All Species:
30.3
Human Site:
S481
Identified Species:
60.61
UniProt:
Q86WB0
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WB0
NP_057562.3
502
55262
S481
P
A
E
T
D
S
M
S
L
S
E
K
S
R
K
Chimpanzee
Pan troglodytes
XP_001156206
502
55199
S481
P
A
E
T
D
S
M
S
L
S
E
K
S
R
K
Rhesus Macaque
Macaca mulatta
XP_001094530
502
55199
S481
P
A
E
T
D
S
M
S
L
S
E
K
S
R
K
Dog
Lupus familis
XP_532428
589
65257
S568
P
A
E
T
D
S
M
S
L
S
E
K
S
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80YV2
501
55178
S480
P
A
E
T
D
S
M
S
L
S
E
K
S
R
K
Rat
Rattus norvegicus
NP_001120765
501
55306
S480
P
A
E
T
D
S
M
S
L
S
E
K
S
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510194
625
67731
G541
P
A
D
T
D
S
M
G
L
V
Q
R
P
A
R
Chicken
Gallus gallus
XP_414975
484
53210
S463
V
P
E
T
E
P
V
S
L
S
V
K
S
C
K
Frog
Xenopus laevis
Q6P7H4
477
53273
S456
I
S
N
P
D
T
S
S
V
P
E
K
S
H
K
Zebra Danio
Brachydanio rerio
NP_001070846
492
54140
Q469
P
V
G
A
S
P
S
Q
G
P
H
D
K
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200598
300
33790
Q280
R
P
A
W
H
G
L
Q
V
L
L
H
E
R
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141693
698
76497
T595
S
R
S
T
E
V
S
T
I
T
E
S
L
V
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
79.2
N.A.
85
85.8
N.A.
53.4
62.3
52.1
43
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.1
99
81.4
N.A.
91
91.2
N.A.
63.3
74.5
65.3
61.9
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
46.6
53.3
40
13.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
73.3
66.6
60
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
40
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
9
9
0
0
0
0
0
0
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
9
0
67
0
0
0
0
0
0
9
0
0
0
% D
% Glu:
0
0
59
0
17
0
0
0
0
0
67
0
9
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
9
0
9
9
0
0
0
0
0
0
% G
% His:
0
0
0
0
9
0
0
0
0
0
9
9
0
9
0
% H
% Ile:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
67
9
0
75
% K
% Leu:
0
0
0
0
0
0
9
0
67
9
9
0
9
0
0
% L
% Met:
0
0
0
0
0
0
59
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% N
% Pro:
67
17
0
9
0
17
0
0
0
17
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
9
0
0
0
0
% Q
% Arg:
9
9
0
0
0
0
0
0
0
0
0
9
0
59
9
% R
% Ser:
9
9
9
0
9
59
25
67
0
59
0
9
67
9
9
% S
% Thr:
0
0
0
75
0
9
0
9
0
9
0
0
0
0
0
% T
% Val:
9
9
0
0
0
9
9
0
17
9
9
0
0
9
0
% V
% Trp:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _