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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZC3HC1
All Species:
16.36
Human Site:
T229
Identified Species:
32.73
UniProt:
Q86WB0
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WB0
NP_057562.3
502
55262
T229
E
D
E
L
D
H
R
T
D
E
R
K
T
T
I
Chimpanzee
Pan troglodytes
XP_001156206
502
55199
T229
E
D
E
L
D
H
R
T
D
E
R
K
T
T
I
Rhesus Macaque
Macaca mulatta
XP_001094530
502
55199
T229
E
D
E
L
D
H
R
T
D
E
R
K
T
T
I
Dog
Lupus familis
XP_532428
589
65257
T316
E
D
E
L
D
C
R
T
E
E
R
K
T
T
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80YV2
501
55178
A229
E
D
E
L
D
F
H
A
D
D
R
K
T
T
S
Rat
Rattus norvegicus
NP_001120765
501
55306
I229
E
D
E
L
D
F
Q
I
D
D
R
K
T
T
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510194
625
67731
T288
E
D
E
L
E
H
R
T
D
G
D
R
A
A
V
Chicken
Gallus gallus
XP_414975
484
53210
I213
I
S
L
L
L
Q
L
I
K
E
E
L
E
H
R
Frog
Xenopus laevis
Q6P7H4
477
53273
V207
M
D
I
T
E
D
T
V
S
R
L
L
R
L
I
Zebra Danio
Brachydanio rerio
NP_001070846
492
54140
K220
L
I
E
D
E
Q
A
K
Q
G
S
S
P
S
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001200598
300
33790
Q32
V
D
E
I
S
S
E
Q
S
S
T
V
Q
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001141693
698
76497
F266
I
K
D
L
D
D
A
F
Q
D
A
D
T
Y
Y
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.8
79.2
N.A.
85
85.8
N.A.
53.4
62.3
52.1
43
N.A.
N.A.
N.A.
N.A.
26.4
Protein Similarity:
100
99.1
99
81.4
N.A.
91
91.2
N.A.
63.3
74.5
65.3
61.9
N.A.
N.A.
N.A.
N.A.
38
P-Site Identity:
100
100
100
80
N.A.
66.6
66.6
N.A.
53.3
13.3
13.3
6.6
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
80
N.A.
73.3
13.3
20
20
N.A.
N.A.
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
22
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
35.5
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
17
9
0
0
9
0
9
9
0
% A
% Cys:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
75
9
9
59
17
0
0
50
25
9
9
0
0
0
% D
% Glu:
59
0
75
0
25
0
9
0
9
42
9
0
9
0
0
% E
% Phe:
0
0
0
0
0
17
0
9
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% G
% His:
0
0
0
0
0
34
9
0
0
0
0
0
0
9
0
% H
% Ile:
17
9
9
9
0
0
0
17
0
0
0
0
0
0
34
% I
% Lys:
0
9
0
0
0
0
0
9
9
0
0
50
0
0
9
% K
% Leu:
9
0
9
75
9
0
9
0
0
0
9
17
0
9
9
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% P
% Gln:
0
0
0
0
0
17
9
9
17
0
0
0
9
0
0
% Q
% Arg:
0
0
0
0
0
0
42
0
0
9
50
9
9
0
9
% R
% Ser:
0
9
0
0
9
9
0
0
17
9
9
9
0
9
25
% S
% Thr:
0
0
0
9
0
0
9
42
0
0
9
0
59
50
0
% T
% Val:
9
0
0
0
0
0
0
9
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _