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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FCHSD1
All Species:
22.73
Human Site:
S435
Identified Species:
55.56
UniProt:
Q86WN1
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WN1
NP_258260.1
690
76942
S435
R
L
S
Q
R
D
L
S
P
T
A
E
D
A
E
Chimpanzee
Pan troglodytes
XP_517998
708
78893
S453
R
L
S
Q
R
D
L
S
P
T
A
E
D
A
E
Rhesus Macaque
Macaca mulatta
XP_001089589
683
76013
S489
R
L
S
Q
R
D
L
S
P
T
A
E
D
A
E
Dog
Lupus familis
XP_544315
692
76848
S437
R
L
S
Q
R
D
L
S
P
T
A
E
D
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6PFY1
688
76237
S433
R
L
S
Q
R
D
L
S
P
T
A
E
D
A
E
Rat
Rattus norvegicus
NP_001103351
690
76749
S435
R
L
S
Q
R
D
L
S
P
T
A
E
D
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517286
382
42400
N204
G
D
L
S
G
R
L
N
D
H
V
A
L
L
G
Chicken
Gallus gallus
XP_425188
790
86565
D505
T
E
A
P
T
G
L
D
P
T
E
F
D
D
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_648290
795
89574
A509
A
A
S
S
S
M
M
A
S
S
A
G
G
W
D
Honey Bee
Apis mellifera
XP_392840
975
109344
L508
E
K
Q
R
I
E
Q
L
T
V
G
W
D
D
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
83.9
88.5
91
N.A.
91
90.7
N.A.
38.9
43.4
N.A.
N.A.
N.A.
25.6
25.1
N.A.
N.A.
Protein Similarity:
100
86.4
89.4
93.2
N.A.
93.4
93.7
N.A.
45.2
57.5
N.A.
N.A.
N.A.
44.9
40.9
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
6.6
26.6
N.A.
N.A.
N.A.
13.3
6.6
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
13.3
33.3
N.A.
N.A.
N.A.
40
20
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
10
0
0
0
0
10
0
0
70
10
0
60
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
0
0
60
0
10
10
0
0
0
80
20
10
% D
% Glu:
10
10
0
0
0
10
0
0
0
0
10
60
0
0
60
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% F
% Gly:
10
0
0
0
10
10
0
0
0
0
10
10
10
0
10
% G
% His:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
60
10
0
0
0
80
10
0
0
0
0
10
10
0
% L
% Met:
0
0
0
0
0
10
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
0
0
70
0
0
0
0
0
10
% P
% Gln:
0
0
10
60
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
60
0
0
10
60
10
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
70
20
10
0
0
60
10
10
0
0
0
0
0
% S
% Thr:
10
0
0
0
10
0
0
0
10
70
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _