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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NR2C2AP All Species: 21.21
Human Site: T116 Identified Species: 42.42
UniProt: Q86WQ0 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WQ0 NP_795361.1 139 15876 T116 E V D R L K V T F E D A T D F
Chimpanzee Pan troglodytes XP_001140169 139 15890 T116 E V D R L K V T F E D A T D F
Rhesus Macaque Macaca mulatta XP_001115092 139 15825 T116 E V D R L K V T F E D A T D F
Dog Lupus familis XP_852149 139 15883 T116 E V D Q L K V T F E D T T D F
Cat Felis silvestris
Mouse Mus musculus Q3TV70 140 15838 T116 E V D R L K L T F E D T T D F
Rat Rattus norvegicus NP_001040569 159 17681 K116 G R D L V F Y K L W V F G C G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_423447 186 21323 T163 A L D T L K I T F E N S I D F
Frog Xenopus laevis Q3B8C3 136 15434 I115 Q S V S K L R I S F L N S T D
Zebra Danio Brachydanio rerio Q1ED21 141 16112 I116 P L V Q K L K I V F E N S T D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_001097439 139 15875 K117 E N P C S K L K F V F E S S T
Honey Bee Apis mellifera XP_001123143 135 15947 F114 I K A K T F K F I F N E S T D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001194956 105 11839 E84 V E G S L P G E R P K K L M D
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 96.4 92 N.A. 82.1 57.8 N.A. N.A. 24.7 57.5 62.4 N.A. 42.4 41.7 N.A. 39.5
Protein Similarity: 100 99.2 98.5 97.1 N.A. 90.7 67.9 N.A. N.A. 39.2 71.2 80.1 N.A. 60.4 58.9 N.A. 55.4
P-Site Identity: 100 100 100 86.6 N.A. 86.6 6.6 N.A. N.A. 53.3 0 0 N.A. 20 0 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 13.3 N.A. N.A. 80 13.3 26.6 N.A. 33.3 20 N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 0 0 0 0 0 25 0 0 0 % A
% Cys: 0 0 0 9 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 59 0 0 0 0 0 0 0 42 0 0 50 34 % D
% Glu: 50 9 0 0 0 0 0 9 0 50 9 17 0 0 0 % E
% Phe: 0 0 0 0 0 17 0 9 59 25 9 9 0 0 50 % F
% Gly: 9 0 9 0 0 0 9 0 0 0 0 0 9 0 9 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 9 0 0 0 0 0 9 17 9 0 0 0 9 0 0 % I
% Lys: 0 9 0 9 17 59 17 17 0 0 9 9 0 0 0 % K
% Leu: 0 17 0 9 59 17 17 0 9 0 9 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % M
% Asn: 0 9 0 0 0 0 0 0 0 0 17 17 0 0 0 % N
% Pro: 9 0 9 0 0 9 0 0 0 9 0 0 0 0 0 % P
% Gln: 9 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 9 0 34 0 0 9 0 9 0 0 0 0 0 0 % R
% Ser: 0 9 0 17 9 0 0 0 9 0 0 9 34 9 0 % S
% Thr: 0 0 0 9 9 0 0 50 0 0 0 17 42 25 9 % T
% Val: 9 42 17 0 9 0 34 0 9 9 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _