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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC25 All Species: 25.15
Human Site: S13 Identified Species: 39.52
UniProt: Q86WR0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WR0 NP_060716.2 208 24479 S13 T S S S V N S S A Y T I Y M G
Chimpanzee Pan troglodytes XP_519679 469 53341 S274 T S S S V N S S A Y T I Y M G
Rhesus Macaque Macaca mulatta XP_001110749 402 45396 S207 T S S S V N S S A Y T I Y M G
Dog Lupus familis XP_850388 256 29606 S61 T S S S V N S S A Y T I Y M G
Cat Felis silvestris
Mouse Mus musculus Q78PG9 208 24461 S13 T S S S V N S S T Y T I Y M G
Rat Rattus norvegicus NP_001101852 208 24447 S13 T S S S V N S S T Y T I Y M G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508888 679 75804 I461 T S P A M W L I S Q Y T R Q L
Chicken Gallus gallus
Frog Xenopus laevis NP_001080284 206 24185 A13 T S D V I S P A Y T I Y M G K
Zebra Danio Brachydanio rerio Q7T312 207 24361 P13 T S A V V S P P H T I Y M G K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572377 209 24770 P13 K S N V V Q P P A M L Y M G R
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189040 196 23221 P13 T S N V V S P P T Y T I Y M G
Poplar Tree Populus trichocarpa XP_002309559 215 25072 D13 K A R P E A G D Y T I F M G L
Maize Zea mays NP_001150110 215 25043 Y14 A R P E A G D Y T I F M G L D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196711 215 25081 D13 K A R P D A G D Y T I F M G L
Baker's Yeast Sacchar. cerevisiae P40206 208 24647 T14 S K P T E Y S T P Y Q I V M G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 51.4 79.6 N.A. 95.6 95.1 N.A. 28.1 N.A. 85.5 79.8 N.A. 56.4 N.A. N.A. 63.9
Protein Similarity: 100 44.3 51.7 80.8 N.A. 98 98 N.A. 29.7 N.A. 93.7 92.3 N.A. 75.5 N.A. N.A. 75.9
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 13.3 N.A. 13.3 20 N.A. 20 N.A. N.A. 60
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 33.3 N.A. 33.3 33.3 N.A. 26.6 N.A. N.A. 73.3
Percent
Protein Identity: 59 57.2 N.A. 60 34.1 N.A.
Protein Similarity: 75.8 75.8 N.A. 78.1 56.7 N.A.
P-Site Identity: 0 0 N.A. 0 33.3 N.A.
P-Site Similarity: 6.6 13.3 N.A. 6.6 53.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 14 7 7 7 14 0 7 34 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 7 0 7 0 7 14 0 0 0 0 0 0 7 % D
% Glu: 0 0 0 7 14 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 7 14 0 0 0 % F
% Gly: 0 0 0 0 0 7 14 0 0 0 0 0 7 34 54 % G
% His: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 7 0 0 7 0 7 27 54 0 0 0 % I
% Lys: 20 7 0 0 0 0 0 0 0 0 0 0 0 0 14 % K
% Leu: 0 0 0 0 0 0 7 0 0 0 7 0 0 7 20 % L
% Met: 0 0 0 0 7 0 0 0 0 7 0 7 34 54 0 % M
% Asn: 0 0 14 0 0 40 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 20 14 0 0 27 20 7 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 7 0 0 0 7 7 0 0 7 0 % Q
% Arg: 0 7 14 0 0 0 0 0 0 0 0 0 7 0 7 % R
% Ser: 7 74 40 40 0 20 47 40 7 0 0 0 0 0 0 % S
% Thr: 67 0 0 7 0 0 0 7 27 27 47 7 0 0 0 % T
% Val: 0 0 0 27 60 0 0 0 0 0 0 0 7 0 0 % V
% Trp: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 7 0 7 20 54 7 20 47 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _