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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC25
All Species:
40.61
Human Site:
S185
Identified Species:
63.81
UniProt:
Q86WR0
Number Species:
14
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WR0
NP_060716.2
208
24479
S185
R
E
M
D
E
L
R
S
Y
S
S
L
M
K
V
Chimpanzee
Pan troglodytes
XP_519679
469
53341
S446
R
E
M
D
E
L
R
S
Y
S
S
L
M
K
V
Rhesus Macaque
Macaca mulatta
XP_001110749
402
45396
S379
R
E
M
D
E
L
R
S
Y
S
S
L
M
K
V
Dog
Lupus familis
XP_850388
256
29606
S233
R
E
M
D
E
L
R
S
Y
S
S
L
M
K
V
Cat
Felis silvestris
Mouse
Mus musculus
Q78PG9
208
24461
S185
R
E
M
D
E
L
R
S
Y
S
S
L
M
K
V
Rat
Rattus norvegicus
NP_001101852
208
24447
S185
R
E
M
D
E
L
R
S
Y
S
S
L
M
K
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508888
679
75804
S656
K
E
M
D
E
L
R
S
Y
S
S
L
M
K
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080284
206
24185
S183
K
E
M
E
E
L
R
S
Y
S
S
L
M
K
S
Zebra Danio
Brachydanio rerio
Q7T312
207
24361
N184
K
E
M
E
D
L
K
N
Y
T
S
L
M
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572377
209
24770
S185
E
L
E
A
E
L
R
S
Y
A
S
L
Q
K
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189040
196
23221
N170
K
A
D
K
E
L
R
N
Y
T
S
L
M
K
E
Poplar Tree
Populus trichocarpa
XP_002309559
215
25072
S184
E
R
Q
A
E
M
R
S
Y
K
G
L
M
V
A
Maize
Zea mays
NP_001150110
215
25043
S184
E
K
Q
A
D
I
R
S
Y
K
G
L
M
V
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196711
215
25081
S184
E
R
Q
S
E
M
R
S
Y
K
G
L
M
V
T
Baker's Yeast
Sacchar. cerevisiae
P40206
208
24647
K183
I
E
E
E
K
L
R
K
V
A
K
K
N
Q
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
51.4
79.6
N.A.
95.6
95.1
N.A.
28.1
N.A.
85.5
79.8
N.A.
56.4
N.A.
N.A.
63.9
Protein Similarity:
100
44.3
51.7
80.8
N.A.
98
98
N.A.
29.7
N.A.
93.7
92.3
N.A.
75.5
N.A.
N.A.
75.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
86.6
N.A.
80
53.3
N.A.
53.3
N.A.
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
93.3
93.3
N.A.
60
N.A.
N.A.
73.3
Percent
Protein Identity:
59
57.2
N.A.
60
34.1
N.A.
Protein Similarity:
75.8
75.8
N.A.
78.1
56.7
N.A.
P-Site Identity:
40
33.3
N.A.
40
20
N.A.
P-Site Similarity:
46.6
53.3
N.A.
46.6
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
20
0
0
0
0
0
14
0
0
0
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
47
14
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
27
67
14
20
80
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
20
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% I
% Lys:
27
7
0
7
7
0
7
7
0
20
7
7
0
74
7
% K
% Leu:
0
7
0
0
0
80
0
0
0
0
0
94
0
0
0
% L
% Met:
0
0
60
0
0
14
0
0
0
0
0
0
87
0
0
% M
% Asn:
0
0
0
0
0
0
0
14
0
0
0
0
7
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
20
0
0
0
0
0
0
0
0
0
7
7
7
% Q
% Arg:
40
14
0
0
0
0
94
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
7
0
0
0
80
0
54
74
0
0
0
27
% S
% Thr:
0
0
0
0
0
0
0
0
0
14
0
0
0
0
7
% T
% Val:
0
0
0
0
0
0
0
0
7
0
0
0
0
20
40
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
94
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _