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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CCDC25
All Species:
38.41
Human Site:
S204
Identified Species:
60.36
UniProt:
Q86WR0
Number Species:
14
Phosphosite Substitution
Charge Score:
0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WR0
NP_060716.2
208
24479
S204
S
N
Q
D
G
N
D
S
D
E
F
M
_
_
_
Chimpanzee
Pan troglodytes
XP_519679
469
53341
S465
S
N
Q
D
G
N
D
S
D
E
F
M
_
_
_
Rhesus Macaque
Macaca mulatta
XP_001110749
402
45396
S398
S
N
Q
D
G
N
D
S
D
E
F
M
_
_
_
Dog
Lupus familis
XP_850388
256
29606
S252
S
N
Q
D
G
N
D
S
D
E
F
M
_
_
_
Cat
Felis silvestris
Mouse
Mus musculus
Q78PG9
208
24461
S204
S
N
Q
D
G
N
D
S
D
E
F
M
_
_
_
Rat
Rattus norvegicus
NP_001101852
208
24447
S204
S
N
Q
D
G
N
D
S
D
E
F
M
_
_
_
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508888
679
75804
S675
S
N
Q
D
G
N
D
S
D
E
F
M
_
_
_
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080284
206
24185
S202
S
N
Q
D
G
N
D
S
D
D
F
M
_
_
_
Zebra Danio
Brachydanio rerio
Q7T312
207
24361
S203
T
N
E
D
G
Y
D
S
D
D
F
M
_
_
_
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572377
209
24770
E204
T
N
Y
D
A
G
N
E
S
D
D
F
M
_
_
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001189040
196
23221
E189
S
N
A
E
N
T
V
E
D
L
E
D
D
F
M
Poplar Tree
Populus trichocarpa
XP_002309559
215
25072
E203
S
N
K
Q
I
A
S
E
N
K
S
L
Q
E
L
Maize
Zea mays
NP_001150110
215
25043
G203
S
N
K
Q
I
A
S
G
S
K
T
L
Q
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196711
215
25081
S203
S
N
K
D
I
A
S
S
N
K
S
L
Q
E
L
Baker's Yeast
Sacchar. cerevisiae
P40206
208
24647
D202
Q
S
K
D
E
V
T
D
D
M
Q
L
E
V
_
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
44.3
51.4
79.6
N.A.
95.6
95.1
N.A.
28.1
N.A.
85.5
79.8
N.A.
56.4
N.A.
N.A.
63.9
Protein Similarity:
100
44.3
51.7
80.8
N.A.
98
98
N.A.
29.7
N.A.
93.7
92.3
N.A.
75.5
N.A.
N.A.
75.9
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
91.6
66.6
N.A.
15.3
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
100
91.6
N.A.
38.4
N.A.
N.A.
26.6
Percent
Protein Identity:
59
57.2
N.A.
60
34.1
N.A.
Protein Similarity:
75.8
75.8
N.A.
78.1
56.7
N.A.
P-Site Identity:
13.3
13.3
N.A.
26.6
14.2
N.A.
P-Site Similarity:
40
33.3
N.A.
53.3
35.7
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
20
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
80
0
0
60
7
74
20
7
7
7
0
0
% D
% Glu:
0
0
7
7
7
0
0
20
0
47
7
0
7
20
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
60
7
0
7
0
% F
% Gly:
0
0
0
0
60
7
0
7
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
27
0
0
0
0
0
0
20
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
7
0
27
0
0
20
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
60
7
0
7
% M
% Asn:
0
94
0
0
7
54
7
0
14
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
7
0
54
14
0
0
0
0
0
0
7
0
20
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
80
7
0
0
0
0
20
67
14
0
14
0
0
0
0
% S
% Thr:
14
0
0
0
0
7
7
0
0
0
7
0
0
0
0
% T
% Val:
0
0
0
0
0
7
7
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
60
67
74
% _