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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC25 All Species: 26.97
Human Site: Y24 Identified Species: 42.38
UniProt: Q86WR0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.36
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WR0 NP_060716.2 208 24479 Y24 I Y M G K D K Y E N E D L I K
Chimpanzee Pan troglodytes XP_519679 469 53341 Y285 I Y M G K D K Y E N E D L I K
Rhesus Macaque Macaca mulatta XP_001110749 402 45396 Y218 I Y M G K D K Y E N E D L I K
Dog Lupus familis XP_850388 256 29606 Y72 I Y M G K D K Y E N E D L I K
Cat Felis silvestris
Mouse Mus musculus Q78PG9 208 24461 Y24 I Y M G K D K Y E N E D L I K
Rat Rattus norvegicus NP_001101852 208 24447 Y24 I Y M G K D K Y E N E D L I K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508888 679 75804 H472 T R Q L F D H H K S K F R Q K
Chicken Gallus gallus
Frog Xenopus laevis NP_001080284 206 24185 E24 Y M G K D K Y E N E D L I K Y
Zebra Danio Brachydanio rerio Q7T312 207 24361 E24 Y M G K D K Y E N E D L I K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572377 209 24770 E24 Y M G R D K H E N E E L I R W
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189040 196 23221 Y24 I Y M G L D K Y E N E D L I K
Poplar Tree Populus trichocarpa XP_002309559 215 25072 E24 F M G L D K H E N E E L I K Y
Maize Zea mays NP_001150110 215 25043 N25 M G L D K Y E N E D L I K Y G
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196711 215 25081 E24 F M G L D K F E N E E L I K Y
Baker's Yeast Sacchar. cerevisiae P40206 208 24647 F25 I V M G K D K F E N D L L I K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 51.4 79.6 N.A. 95.6 95.1 N.A. 28.1 N.A. 85.5 79.8 N.A. 56.4 N.A. N.A. 63.9
Protein Similarity: 100 44.3 51.7 80.8 N.A. 98 98 N.A. 29.7 N.A. 93.7 92.3 N.A. 75.5 N.A. N.A. 75.9
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 N.A. 0 0 N.A. 6.6 N.A. N.A. 93.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 40 N.A. 13.3 13.3 N.A. 13.3 N.A. N.A. 93.3
Percent
Protein Identity: 59 57.2 N.A. 60 34.1 N.A.
Protein Similarity: 75.8 75.8 N.A. 78.1 56.7 N.A.
P-Site Identity: 6.6 13.3 N.A. 6.6 73.3 N.A.
P-Site Similarity: 13.3 40 N.A. 13.3 86.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 34 60 0 0 0 7 20 47 0 0 0 % D
% Glu: 0 0 0 0 0 0 7 34 60 34 67 0 0 0 0 % E
% Phe: 14 0 0 0 7 0 7 7 0 0 0 7 0 0 0 % F
% Gly: 0 7 34 54 0 0 0 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 0 0 20 7 0 0 0 0 0 0 0 % H
% Ile: 54 0 0 0 0 0 0 0 0 0 0 7 34 54 0 % I
% Lys: 0 0 0 14 54 34 54 0 7 0 7 0 7 27 60 % K
% Leu: 0 0 7 20 7 0 0 0 0 0 7 40 54 0 0 % L
% Met: 7 34 54 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 7 34 54 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 7 0 % Q
% Arg: 0 7 0 7 0 0 0 0 0 0 0 0 7 7 0 % R
% Ser: 0 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % S
% Thr: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % W
% Tyr: 20 47 0 0 0 7 14 47 0 0 0 0 0 7 27 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _