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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC25 All Species: 55.45
Human Site: Y51 Identified Species: 87.14
UniProt: Q86WR0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WR0 NP_060716.2 208 24479 Y51 K L S S A H V Y L R L H K G E
Chimpanzee Pan troglodytes XP_519679 469 53341 Y312 K L S S A H V Y L R L H K G E
Rhesus Macaque Macaca mulatta XP_001110749 402 45396 Y245 K L S S A H V Y L R L H K G E
Dog Lupus familis XP_850388 256 29606 Y99 K L S S A H V Y L R L H K G E
Cat Felis silvestris
Mouse Mus musculus Q78PG9 208 24461 Y51 K L S S A H V Y L R L Q K G E
Rat Rattus norvegicus NP_001101852 208 24447 Y51 K L S S A H V Y L R L Q K G E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508888 679 75804 Y522 K L S S A H V Y L R L H K G E
Chicken Gallus gallus
Frog Xenopus laevis NP_001080284 206 24185 Y50 K L S S A H V Y L R L Q K G Q
Zebra Danio Brachydanio rerio Q7T312 207 24361 Y50 K L S S A H V Y L R M P K G T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572377 209 24770 Y50 D L S S A H V Y L R L R K G Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189040 196 23221 H49 V D K L S S A H V Y L R L K K
Poplar Tree Populus trichocarpa XP_002309559 215 25072 Y50 K M S S A H V Y L R L H K G Q
Maize Zea mays NP_001150110 215 25043 Y50 K M S S A H V Y V R L N K G Q
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196711 215 25081 Y50 K M S S A H V Y L R L H R G Q
Baker's Yeast Sacchar. cerevisiae P40206 208 24647 Y54 K Y S S G H V Y L K L R P N E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 51.4 79.6 N.A. 95.6 95.1 N.A. 28.1 N.A. 85.5 79.8 N.A. 56.4 N.A. N.A. 63.9
Protein Similarity: 100 44.3 51.7 80.8 N.A. 98 98 N.A. 29.7 N.A. 93.7 92.3 N.A. 75.5 N.A. N.A. 75.9
P-Site Identity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 N.A. 86.6 80 N.A. 80 N.A. N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 100 N.A. 93.3 86.6 N.A. 86.6 N.A. N.A. 33.3
Percent
Protein Identity: 59 57.2 N.A. 60 34.1 N.A.
Protein Similarity: 75.8 75.8 N.A. 78.1 56.7 N.A.
P-Site Identity: 86.6 73.3 N.A. 80 60 N.A.
P-Site Similarity: 100 100 N.A. 100 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 87 0 7 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 7 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 54 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 0 0 0 87 0 % G
% His: 0 0 0 0 0 94 0 7 0 0 0 47 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 87 0 7 0 0 0 0 0 0 7 0 0 80 7 7 % K
% Leu: 0 67 0 7 0 0 0 0 87 0 94 0 7 0 0 % L
% Met: 0 20 0 0 0 0 0 0 0 0 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 7 0 7 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 7 7 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 20 0 0 34 % Q
% Arg: 0 0 0 0 0 0 0 0 0 87 0 20 7 0 0 % R
% Ser: 0 0 94 94 7 7 0 0 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % T
% Val: 7 0 0 0 0 0 94 0 14 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 0 0 94 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _