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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CCDC25 All Species: 57.58
Human Site: Y92 Identified Species: 90.48
UniProt: Q86WR0 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WR0 NP_060716.2 208 24479 Y92 M N N V N V V Y T P W S N L K
Chimpanzee Pan troglodytes XP_519679 469 53341 Y353 M N N V N V V Y T P W S N L K
Rhesus Macaque Macaca mulatta XP_001110749 402 45396 Y286 M N N V N V V Y T P W S N L K
Dog Lupus familis XP_850388 256 29606 Y140 M N N V N V V Y T P W A N L K
Cat Felis silvestris
Mouse Mus musculus Q78PG9 208 24461 Y92 M N N V N V V Y T P W S N L K
Rat Rattus norvegicus NP_001101852 208 24447 Y92 M N N V N V V Y T P W S N L K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508888 679 75804 Y563 M N N I N V V Y T P W S N L K
Chicken Gallus gallus
Frog Xenopus laevis NP_001080284 206 24185 Y91 M N N L N V V Y T P W A N L K
Zebra Danio Brachydanio rerio Q7T312 207 24361 Y91 M N N I N I V Y T P W S N L K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572377 209 24770 Y91 V N N L E V V Y T M W E N L K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001189040 196 23221 Y77 M N N I A V V Y T P W A N L K
Poplar Tree Populus trichocarpa XP_002309559 215 25072 Y91 V N N I D V V Y T P W A N L K
Maize Zea mays NP_001150110 215 25043 Y91 V N N I D V V Y T P W Y N L K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_196711 215 25081 Y91 V N N V D V V Y T P W S N L K
Baker's Yeast Sacchar. cerevisiae P40206 208 24647 I96 M P Q C T I L I T P W H N L R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 44.3 51.4 79.6 N.A. 95.6 95.1 N.A. 28.1 N.A. 85.5 79.8 N.A. 56.4 N.A. N.A. 63.9
Protein Similarity: 100 44.3 51.7 80.8 N.A. 98 98 N.A. 29.7 N.A. 93.7 92.3 N.A. 75.5 N.A. N.A. 75.9
P-Site Identity: 100 100 100 93.3 N.A. 100 100 N.A. 93.3 N.A. 86.6 86.6 N.A. 66.6 N.A. N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 100 N.A. 100 100 N.A. 80 N.A. N.A. 93.3
Percent
Protein Identity: 59 57.2 N.A. 60 34.1 N.A.
Protein Similarity: 75.8 75.8 N.A. 78.1 56.7 N.A.
P-Site Identity: 73.3 73.3 N.A. 86.6 40 N.A.
P-Site Similarity: 100 93.3 N.A. 100 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 7 0 0 0 0 0 0 27 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 20 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 7 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 0 0 0 34 0 14 0 7 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 94 % K
% Leu: 0 0 0 14 0 0 7 0 0 0 0 0 0 100 0 % L
% Met: 74 0 0 0 0 0 0 0 0 7 0 0 0 0 0 % M
% Asn: 0 94 94 0 60 0 0 0 0 0 0 0 100 0 0 % N
% Pro: 0 7 0 0 0 0 0 0 0 94 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % R
% Ser: 0 0 0 0 0 0 0 0 0 0 0 54 0 0 0 % S
% Thr: 0 0 0 0 7 0 0 0 100 0 0 0 0 0 0 % T
% Val: 27 0 0 47 0 87 94 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 94 0 0 0 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _