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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMPRSS12
All Species:
10
Human Site:
S24
Identified Species:
31.43
UniProt:
Q86WS5
Number Species:
7
Phosphosite Substitution
Charge Score:
0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WS5
NP_872365.1
348
38604
S24
H
L
Y
S
D
H
Y
S
P
S
G
R
H
R
L
Chimpanzee
Pan troglodytes
XP_522598
348
38412
S24
H
S
Y
S
D
H
Y
S
P
S
G
R
H
R
L
Rhesus Macaque
Macaca mulatta
XP_001083472
348
38620
S24
H
L
H
S
D
H
N
S
P
P
G
R
H
S
L
Dog
Lupus familis
XP_850699
417
45485
W69
L
P
Y
S
G
H
D
W
L
S
E
R
T
G
R
Cat
Felis silvestris
Mouse
Mus musculus
Q3V0Q7
336
36898
S24
F
A
Y
S
E
L
H
S
L
S
L
R
E
G
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521713
288
31706
Chicken
Gallus gallus
XP_424480
355
38408
V34
W
M
S
L
E
V
L
V
E
C
G
R
R
P
L
Frog
Xenopus laevis
NP_001089555
461
52256
E24
E
T
R
G
G
R
L
E
H
M
L
P
G
Q
S
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.8
92.2
58.9
N.A.
59.7
N.A.
N.A.
40.5
33.7
28.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
98.8
94.2
68.5
N.A.
74.1
N.A.
N.A.
59.2
47.8
37.9
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
73.3
33.3
N.A.
33.3
N.A.
N.A.
0
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
93.3
80
33.3
N.A.
46.6
N.A.
N.A.
0
33.3
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% C
% Asp:
0
0
0
0
38
0
13
0
0
0
0
0
0
0
0
% D
% Glu:
13
0
0
0
25
0
0
13
13
0
13
0
13
0
0
% E
% Phe:
13
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
13
25
0
0
0
0
0
50
0
13
25
0
% G
% His:
38
0
13
0
0
50
13
0
13
0
0
0
38
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
13
25
0
13
0
13
25
0
25
0
25
0
0
0
50
% L
% Met:
0
13
0
0
0
0
0
0
0
13
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
13
0
0
0
0
0
0
0
0
% N
% Pro:
0
13
0
0
0
0
0
0
38
13
0
13
0
13
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
13
0
% Q
% Arg:
0
0
13
0
0
13
0
0
0
0
0
75
13
25
13
% R
% Ser:
0
13
13
63
0
0
0
50
0
50
0
0
0
13
25
% S
% Thr:
0
13
0
0
0
0
0
0
0
0
0
0
13
0
0
% T
% Val:
0
0
0
0
0
13
0
13
0
0
0
0
0
0
0
% V
% Trp:
13
0
0
0
0
0
0
13
0
0
0
0
0
0
0
% W
% Tyr:
0
0
50
0
0
0
25
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _