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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM69
All Species:
16.36
Human Site:
T422
Identified Species:
40
UniProt:
Q86WT6
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WT6
NP_542783.2
500
57419
T422
L
L
R
L
R
N
Q
T
D
L
K
A
L
D
L
Chimpanzee
Pan troglodytes
Q1XHU0
518
59727
D437
R
V
R
L
W
N
G
D
K
Y
A
A
T
T
T
Rhesus Macaque
Macaca mulatta
XP_001110899
499
57126
T421
L
L
R
L
R
N
Q
T
D
L
K
A
L
D
L
Dog
Lupus familis
XP_535459
500
57553
I422
L
L
R
L
R
N
Q
I
D
L
K
A
L
D
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80X56
500
57294
T423
L
L
R
L
R
N
Q
T
D
L
K
A
L
D
L
Rat
Rattus norvegicus
Q5BK82
499
57196
T422
L
L
R
L
R
N
Q
T
D
L
K
A
L
D
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508094
289
33053
E225
L
L
E
E
L
R
E
E
G
K
A
Q
N
Q
E
Chicken
Gallus gallus
XP_425213
516
58097
T437
T
L
R
L
R
N
K
T
E
Y
W
A
T
A
T
Frog
Xenopus laevis
Q91431
610
69096
N532
A
I
W
L
R
N
G
N
R
Y
K
A
L
E
S
Zebra Danio
Brachydanio rerio
NP_001093511
554
63877
E473
T
V
W
L
R
K
N
E
Y
K
A
L
A
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.2
96.4
87.1
N.A.
79
79.8
N.A.
32.4
27.7
38
29.4
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
53.2
98.5
94.4
N.A.
92
92
N.A.
43.2
44.9
52.7
49.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
26.6
100
93.3
N.A.
100
100
N.A.
13.3
46.6
40
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
100
93.3
N.A.
100
100
N.A.
20
60
53.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
0
0
0
30
80
10
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
50
0
0
0
0
50
0
% D
% Glu:
0
0
10
10
0
0
10
20
10
0
0
0
0
10
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
20
0
10
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
10
10
0
10
20
60
0
0
0
0
% K
% Leu:
60
70
0
90
10
0
0
0
0
50
0
10
60
0
50
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
80
10
10
0
0
0
0
10
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% P
% Gln:
0
0
0
0
0
0
50
0
0
0
0
10
0
10
0
% Q
% Arg:
10
0
70
0
80
10
0
0
10
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% S
% Thr:
20
0
0
0
0
0
0
50
0
0
0
0
20
10
20
% T
% Val:
0
20
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
20
0
10
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
30
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _