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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LDHD
All Species:
11.82
Human Site:
S235
Identified Species:
28.89
UniProt:
Q86WU2
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86WU2
NP_705690.2
507
54871
S235
V
S
L
G
R
R
K
S
A
A
G
Y
N
L
T
Chimpanzee
Pan troglodytes
XP_511108
507
54880
S235
V
S
L
G
R
R
K
S
A
A
G
Y
N
L
T
Rhesus Macaque
Macaca mulatta
XP_001103000
490
52661
S218
Q
G
R
H
F
R
K
S
A
A
G
Y
N
L
T
Dog
Lupus familis
XP_852976
483
51580
V222
Y
N
L
T
G
L
F
V
G
S
E
G
T
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q7TNG8
484
51829
L239
I
T
S
T
T
L
R
L
H
P
A
P
E
A
T
Rat
Rattus norvegicus
P84850
535
58786
D259
C
L
T
S
L
R
K
D
N
T
G
Y
D
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A1L258
533
58696
D256
C
L
A
T
L
R
K
D
N
T
G
Y
D
L
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_796456
478
51611
T231
E
G
T
L
G
I
I
T
K
A
T
L
R
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q94AX4
567
62157
S289
T
A
S
R
A
R
K
S
A
A
G
Y
D
L
T
Baker's Yeast
Sacchar. cerevisiae
P32891
587
65274
I316
G
S
E
G
T
L
G
I
V
T
E
A
T
V
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
89.5
80.6
N.A.
81.6
25
N.A.
N.A.
N.A.
N.A.
23.6
N.A.
N.A.
N.A.
N.A.
54
Protein Similarity:
100
100
91.7
86.1
N.A.
87.3
40.5
N.A.
N.A.
N.A.
N.A.
41.4
N.A.
N.A.
N.A.
N.A.
69.2
P-Site Identity:
100
100
66.6
13.3
N.A.
6.6
33.3
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
66.6
26.6
N.A.
26.6
40
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
29.8
26.9
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.5
43.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
10
0
10
0
0
0
40
50
10
10
0
10
0
% A
% Cys:
20
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
20
0
0
0
0
30
0
0
% D
% Glu:
10
0
10
0
0
0
0
0
0
0
20
0
10
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
10
20
0
30
20
0
10
0
10
0
60
10
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
10
10
10
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
60
0
10
0
0
0
0
0
30
% K
% Leu:
0
20
30
10
20
30
0
10
0
0
0
10
0
70
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
10
0
0
0
0
0
0
20
0
0
0
30
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
10
10
20
60
10
0
0
0
0
0
10
0
0
% R
% Ser:
0
30
20
10
0
0
0
40
0
10
0
0
0
0
0
% S
% Thr:
10
10
20
30
20
0
0
10
0
30
10
0
20
0
50
% T
% Val:
20
0
0
0
0
0
0
10
10
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
60
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _