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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: HEATR4 All Species: 8.48
Human Site: T109 Identified Species: 37.33
UniProt: Q86WZ0 Number Species: 5
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86WZ0 NP_976054.1 979 111877 T109 K K S K P A S T V R E A P R P
Chimpanzee Pan troglodytes XP_510047 979 112058 T109 K K S K P A S T V W E A P H P
Rhesus Macaque Macaca mulatta XP_001085412 961 109977 T156 K K S K P A S T V R E A P R P
Dog Lupus familis XP_537505 972 110926 V131 K P K L A R V V H E K P S P G
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus XP_576072 1461 165650 K216 T G F A K T Q K S D G S K K V
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794299 1243 139789 E150 I I P D R D D E I V S E A G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.6 87.9 75.2 N.A. N.A. 44.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 24.7
Protein Similarity: 100 98.9 91 83 N.A. N.A. 54.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 41.6
P-Site Identity: 100 86.6 100 6.6 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 86.6 100 13.3 N.A. N.A. 13.3 N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 17 17 50 0 0 0 0 0 50 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 17 0 17 17 0 0 17 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 17 0 17 50 17 0 0 0 % E
% Phe: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 17 0 0 0 0 0 0 0 0 17 0 0 17 17 % G
% His: 0 0 0 0 0 0 0 0 17 0 0 0 0 17 0 % H
% Ile: 17 17 0 0 0 0 0 0 17 0 0 0 0 0 0 % I
% Lys: 67 50 17 50 17 0 0 17 0 0 17 0 17 17 0 % K
% Leu: 0 0 0 17 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 17 17 0 50 0 0 0 0 0 0 17 50 17 50 % P
% Gln: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 17 17 0 0 0 34 0 0 0 34 0 % R
% Ser: 0 0 50 0 0 0 50 0 17 0 17 17 17 0 0 % S
% Thr: 17 0 0 0 0 17 0 50 0 0 0 0 0 0 17 % T
% Val: 0 0 0 0 0 0 17 17 50 17 0 0 0 0 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 17 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _