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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RALGAPB
All Species:
18.18
Human Site:
S646
Identified Species:
36.36
UniProt:
Q86X10
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X10
NP_065069.1
1494
166799
S646
G
K
F
S
N
D
D
S
S
S
Y
D
K
P
I
Chimpanzee
Pan troglodytes
XP_514640
1544
172643
S699
G
K
F
S
N
D
D
S
S
S
Y
D
K
P
I
Rhesus Macaque
Macaca mulatta
XP_001094087
1630
182005
S785
G
K
F
S
N
D
D
S
S
T
Y
D
K
P
I
Dog
Lupus familis
XP_852604
1495
166840
S646
G
K
F
S
N
D
D
S
S
S
Y
D
K
P
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BQZ4
1484
165181
K641
D
D
S
S
S
Y
D
K
P
I
T
F
L
S
L
Rat
Rattus norvegicus
P86410
1484
165348
K641
D
D
S
S
S
Y
D
K
P
I
T
F
L
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511693
1492
166538
G647
G
K
F
S
N
D
D
G
F
S
N
D
K
P
V
Chicken
Gallus gallus
NP_001026017
1491
166258
S645
G
K
F
S
N
D
D
S
S
T
Y
D
K
P
V
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_002662611
477
52224
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001138184
1468
162790
M651
T
C
E
S
S
E
K
M
F
T
F
I
Q
L
K
Honey Bee
Apis mellifera
XP_395594
1486
165195
E628
F
I
N
S
M
I
S
E
K
N
H
V
T
F
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784978
825
91579
C31
S
R
S
A
M
Y
M
C
I
L
D
S
A
M
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.3
90.7
98.3
N.A.
95.7
95.4
N.A.
92.5
91.8
N.A.
27.7
N.A.
43.4
44.1
N.A.
26.4
Protein Similarity:
100
96.4
91.2
99.2
N.A.
97.4
97.1
N.A.
96.5
96.2
N.A.
30
N.A.
60.9
61.7
N.A.
37.5
P-Site Identity:
100
100
93.3
100
N.A.
13.3
13.3
N.A.
73.3
86.6
N.A.
0
N.A.
6.6
6.6
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
80
100
N.A.
0
N.A.
40
20
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
9
% A
% Cys:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
0
% C
% Asp:
17
17
0
0
0
50
67
0
0
0
9
50
0
0
0
% D
% Glu:
0
0
9
0
0
9
0
9
0
0
0
0
0
0
0
% E
% Phe:
9
0
50
0
0
0
0
0
17
0
9
17
0
9
0
% F
% Gly:
50
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% H
% Ile:
0
9
0
0
0
9
0
0
9
17
0
9
0
0
34
% I
% Lys:
0
50
0
0
0
0
9
17
9
0
0
0
50
0
9
% K
% Leu:
0
0
0
0
0
0
0
0
0
9
0
0
17
9
17
% L
% Met:
0
0
0
0
17
0
9
9
0
0
0
0
0
9
0
% M
% Asn:
0
0
9
0
50
0
0
0
0
9
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
17
0
0
0
0
50
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% Q
% Arg:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
25
84
25
0
9
42
42
34
0
9
0
17
9
% S
% Thr:
9
0
0
0
0
0
0
0
0
25
17
0
9
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
25
0
0
0
0
42
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _