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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM17
All Species:
15.15
Human Site:
S182
Identified Species:
37.04
UniProt:
Q86X19
Number Species:
9
Phosphosite Substitution
Charge Score:
0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X19
NP_938017.2
198
23046
S182
L
Q
D
F
D
R
L
S
A
N
R
G
D
M
R
Chimpanzee
Pan troglodytes
XP_001161917
198
23042
S182
L
Q
D
F
D
R
L
S
A
K
R
G
D
M
R
Rhesus Macaque
Macaca mulatta
XP_001083080
173
20331
A158
Q
D
F
D
R
L
S
A
N
R
G
D
M
R
R
Dog
Lupus familis
XP_531842
198
23046
S182
L
Q
D
F
D
R
L
S
A
Y
R
G
G
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8K0U3
198
22604
S182
L
Q
D
F
D
Q
L
S
S
S
S
A
A
V
R
Rat
Rattus norvegicus
Q5HZE5
198
22536
S182
L
Q
D
F
D
Q
L
S
A
S
S
A
T
G
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512723
275
31301
D234
L
R
D
F
D
R
L
D
Q
S
S
V
T
R
D
Chicken
Gallus gallus
XP_419352
208
24253
E183
L
N
E
F
D
R
L
E
E
H
P
V
R
H
L
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q502E0
219
25301
Q193
M
R
Q
F
G
H
V
Q
G
L
H
T
A
E
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175842
206
24077
E182
L
Q
Q
F
D
D
I
E
L
M
E
D
S
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.4
85.3
90.4
N.A.
79.8
78.7
N.A.
50.1
60.5
N.A.
40.6
N.A.
N.A.
N.A.
N.A.
45.6
Protein Similarity:
100
99.4
85.8
95.4
N.A.
90.9
88.3
N.A.
60.7
78.8
N.A.
63.4
N.A.
N.A.
N.A.
N.A.
66
P-Site Identity:
100
93.3
6.6
80
N.A.
53.3
60
N.A.
40
33.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
93.3
13.3
86.6
N.A.
80
73.3
N.A.
53.3
46.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
10
40
0
0
20
20
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
60
10
80
10
0
10
0
0
0
20
20
0
10
% D
% Glu:
0
0
10
0
0
0
0
20
10
0
10
0
0
10
0
% E
% Phe:
0
0
10
90
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
10
0
0
0
10
0
10
30
10
10
10
% G
% His:
0
0
0
0
0
10
0
0
0
10
10
0
0
10
0
% H
% Ile:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% K
% Leu:
80
0
0
0
0
10
70
0
10
10
0
0
0
0
10
% L
% Met:
10
0
0
0
0
0
0
0
0
10
0
0
10
20
0
% M
% Asn:
0
10
0
0
0
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% P
% Gln:
10
60
20
0
0
20
0
10
10
0
0
0
0
0
0
% Q
% Arg:
0
20
0
0
10
50
0
0
0
10
30
0
10
20
60
% R
% Ser:
0
0
0
0
0
0
10
50
10
30
30
0
10
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
10
20
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
20
0
20
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _