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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TMEM17 All Species: 16.67
Human Site: S22 Identified Species: 40.74
UniProt: Q86X19 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X19 NP_938017.2 198 23046 S22 S R A V F S D S N R T G P E S
Chimpanzee Pan troglodytes XP_001161917 198 23042 S22 S R A V F S D S N R T G P E S
Rhesus Macaque Macaca mulatta XP_001083080 173 20331 N10 Q L L D I A E N E M V S S L A
Dog Lupus familis XP_531842 198 23046 S22 S R T V F S D S N R T G P E Y
Cat Felis silvestris
Mouse Mus musculus Q8K0U3 198 22604 S22 S L T V F G D S S R T G P E S
Rat Rattus norvegicus Q5HZE5 198 22536 S22 S L T M F G D S S R T G P E S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512723 275 31301 S74 A A Q K R S S S R F P I F P F
Chicken Gallus gallus XP_419352 208 24253 R23 R T V F T D S R R A G P Q Y P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q502E0 219 25301 A33 N N R T R D S A D F K D H Y L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001175842 206 24077 N22 E A V F P T R N A V K R Q H H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.4 85.3 90.4 N.A. 79.8 78.7 N.A. 50.1 60.5 N.A. 40.6 N.A. N.A. N.A. N.A. 45.6
Protein Similarity: 100 99.4 85.8 95.4 N.A. 90.9 88.3 N.A. 60.7 78.8 N.A. 63.4 N.A. N.A. N.A. N.A. 66
P-Site Identity: 100 100 0 86.6 N.A. 73.3 66.6 N.A. 13.3 0 N.A. 0 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 26.6 86.6 N.A. 80 80 N.A. 20 0 N.A. 20 N.A. N.A. N.A. N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 20 20 0 0 10 0 10 10 10 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 10 0 20 50 0 10 0 0 10 0 0 0 % D
% Glu: 10 0 0 0 0 0 10 0 10 0 0 0 0 50 0 % E
% Phe: 0 0 0 20 50 0 0 0 0 20 0 0 10 0 10 % F
% Gly: 0 0 0 0 0 20 0 0 0 0 10 50 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 10 % H
% Ile: 0 0 0 0 10 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 0 0 10 0 0 0 0 0 0 20 0 0 0 0 % K
% Leu: 0 30 10 0 0 0 0 0 0 0 0 0 0 10 10 % L
% Met: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % M
% Asn: 10 10 0 0 0 0 0 20 30 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 10 0 0 0 0 0 10 10 50 10 10 % P
% Gln: 10 0 10 0 0 0 0 0 0 0 0 0 20 0 0 % Q
% Arg: 10 30 10 0 20 0 10 10 20 50 0 10 0 0 0 % R
% Ser: 50 0 0 0 0 40 30 60 20 0 0 10 10 0 40 % S
% Thr: 0 10 30 10 10 10 0 0 0 0 50 0 0 0 0 % T
% Val: 0 0 20 40 0 0 0 0 0 10 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 20 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _