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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LSR
All Species:
5.45
Human Site:
S546
Identified Species:
13.33
UniProt:
Q86X29
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X29
NP_057009.3
649
71439
S546
D
S
R
D
F
P
R
S
R
D
P
H
Y
D
D
Chimpanzee
Pan troglodytes
XP_524221
668
73388
S547
D
S
R
D
F
P
R
S
R
D
P
H
Y
D
D
Rhesus Macaque
Macaca mulatta
XP_001111345
722
77123
T594
Q
R
T
I
A
P
R
T
H
P
Y
S
P
K
I
Dog
Lupus familis
XP_541695
726
79867
P622
G
P
R
E
F
P
H
P
R
D
P
H
Y
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q99KG5
594
66089
P492
D
L
P
H
S
R
D
P
H
Y
Y
D
D
L
R
Rat
Rattus norvegicus
Q9WU74
593
65758
R490
P
R
D
L
P
H
S
R
D
P
H
Y
Y
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521289
154
16701
A52
S
F
C
R
D
R
I
A
D
A
F
S
P
A
S
Chicken
Gallus gallus
XP_416658
744
81759
N585
Y
T
K
R
S
R
G
N
R
E
P
L
T
D
S
Frog
Xenopus laevis
Q32NM7
545
62737
E443
S
D
R
A
R
P
T
E
R
R
R
S
P
E
R
Zebra Danio
Brachydanio rerio
NP_001020643
594
65398
R492
R
D
P
G
R
G
G
R
D
E
Y
D
D
S
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95
56.6
75.4
N.A.
74.7
76.1
N.A.
20.6
31.4
24.1
43.1
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
95.9
63.7
79.6
N.A.
79.6
80.2
N.A.
22.3
45.5
35.9
53.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
13.3
66.6
N.A.
6.6
20
N.A.
0
20
20
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
20
73.3
N.A.
6.6
26.6
N.A.
6.6
46.6
26.6
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
10
0
0
10
0
10
0
0
0
10
0
% A
% Cys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
20
10
20
10
0
10
0
30
30
0
20
20
50
40
% D
% Glu:
0
0
0
10
0
0
0
10
0
20
0
0
0
10
0
% E
% Phe:
0
10
0
0
30
0
0
0
0
0
10
0
0
0
10
% F
% Gly:
10
0
0
10
0
10
20
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
10
0
10
10
0
20
0
10
30
0
0
0
% H
% Ile:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
10
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
0
10
0
10
0
0
0
0
0
0
0
10
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% N
% Pro:
10
10
20
0
10
50
0
20
0
20
40
0
30
0
0
% P
% Gln:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
10
20
40
20
20
30
30
20
50
10
10
0
0
0
20
% R
% Ser:
20
20
0
0
20
0
10
20
0
0
0
30
0
10
20
% S
% Thr:
0
10
10
0
0
0
10
10
0
0
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
10
30
10
40
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _