KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC6
All Species:
13.03
Human Site:
S163
Identified Species:
31.85
UniProt:
Q86X45
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X45
NP_036604.2
466
54255
S163
I
K
A
L
Q
D
Y
S
V
I
E
P
Q
I
R
Chimpanzee
Pan troglodytes
XP_519965
466
54219
S163
I
K
A
L
Q
D
Y
S
V
I
E
P
Q
I
R
Rhesus Macaque
Macaca mulatta
XP_001085271
466
54312
S163
I
K
A
L
Q
E
Y
S
I
I
E
P
Q
I
R
Dog
Lupus familis
XP_862297
469
54552
P163
I
Q
A
L
Q
N
F
P
V
I
E
Q
Q
I
R
Cat
Felis silvestris
Mouse
Mus musculus
O88978
473
55031
T163
I
Q
A
L
Q
N
Y
T
S
V
E
Q
Q
I
R
Rat
Rattus norvegicus
Q6AXZ2
323
35984
L55
D
D
L
E
T
V
R
L
D
G
E
G
I
T
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507499
464
54033
P163
I
Q
A
L
Q
N
Y
P
V
V
E
R
R
I
R
Chicken
Gallus gallus
XP_418433
465
54577
P163
I
Q
A
L
Q
S
Y
P
E
V
K
Q
K
I
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NUW5
250
28117
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791802
460
53216
D163
I
S
A
L
Q
E
V
D
A
I
R
P
K
I
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.2
80.1
N.A.
79.4
21.4
N.A.
65.2
60.5
N.A.
20.3
N.A.
N.A.
N.A.
N.A.
51.5
Protein Similarity:
100
99.1
98.5
86.9
N.A.
87.7
34.9
N.A.
78.5
77.2
N.A.
34.3
N.A.
N.A.
N.A.
N.A.
70.1
P-Site Identity:
100
100
86.6
66.6
N.A.
60
6.6
N.A.
60
46.6
N.A.
0
N.A.
N.A.
N.A.
N.A.
46.6
P-Site Similarity:
100
100
100
86.6
N.A.
86.6
6.6
N.A.
86.6
73.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
80
0
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% C
% Asp:
10
10
0
0
0
20
0
10
10
0
0
0
0
0
0
% D
% Glu:
0
0
0
10
0
20
0
0
10
0
70
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
80
0
0
0
0
0
0
0
10
50
0
0
10
80
0
% I
% Lys:
0
30
0
0
0
0
0
0
0
0
10
0
20
0
0
% K
% Leu:
0
0
10
80
0
0
0
10
0
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
30
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
30
0
0
0
40
0
0
0
% P
% Gln:
0
40
0
0
80
0
0
0
0
0
0
30
50
0
0
% Q
% Arg:
0
0
0
0
0
0
10
0
0
0
10
10
10
0
70
% R
% Ser:
0
10
0
0
0
10
0
30
10
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
10
0
0
10
0
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
10
10
0
40
30
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
60
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _