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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LRRC6
All Species:
12.12
Human Site:
S219
Identified Species:
29.63
UniProt:
Q86X45
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X45
NP_036604.2
466
54255
S219
T
D
I
N
A
T
L
S
S
L
E
S
K
D
H
Chimpanzee
Pan troglodytes
XP_519965
466
54219
S219
T
D
I
N
A
T
L
S
S
L
E
S
K
D
H
Rhesus Macaque
Macaca mulatta
XP_001085271
466
54312
S219
T
D
I
N
A
T
L
S
S
L
E
S
K
D
H
Dog
Lupus familis
XP_862297
469
54552
L219
V
S
T
T
L
H
S
L
E
S
K
D
H
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
O88978
473
55031
T223
H
T
A
C
P
S
A
T
E
N
Q
D
Y
P
Q
Rat
Rattus norvegicus
Q6AXZ2
323
35984
L88
K
I
Q
R
I
E
N
L
A
C
I
T
S
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507499
464
54033
N215
Q
R
W
L
A
V
I
N
N
T
F
P
K
Y
R
Chicken
Gallus gallus
XP_418433
465
54577
S213
L
G
L
D
S
P
D
S
L
Q
Y
K
E
N
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q6NUW5
250
28117
R14
I
S
L
E
L
R
N
R
T
P
A
E
V
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791802
460
53216
D205
K
E
R
K
K
G
F
D
K
T
W
Y
T
D
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97.2
80.1
N.A.
79.4
21.4
N.A.
65.2
60.5
N.A.
20.3
N.A.
N.A.
N.A.
N.A.
51.5
Protein Similarity:
100
99.1
98.5
86.9
N.A.
87.7
34.9
N.A.
78.5
77.2
N.A.
34.3
N.A.
N.A.
N.A.
N.A.
70.1
P-Site Identity:
100
100
100
0
N.A.
0
0
N.A.
13.3
13.3
N.A.
0
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
6.6
N.A.
20
13.3
N.A.
33.3
46.6
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
40
0
10
0
10
0
10
0
0
10
0
% A
% Cys:
0
0
0
10
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
30
0
10
0
0
10
10
0
0
0
20
0
40
0
% D
% Glu:
0
10
0
10
0
10
0
0
20
0
30
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
10
0
0
0
10
0
0
0
0
% F
% Gly:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
10
0
0
0
0
0
0
10
0
40
% H
% Ile:
10
10
30
0
10
0
10
0
0
0
10
0
0
0
10
% I
% Lys:
20
0
0
10
10
0
0
0
10
0
10
10
40
0
0
% K
% Leu:
10
0
20
10
20
0
30
20
10
30
0
0
0
10
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
30
0
0
20
10
10
10
0
0
0
10
0
% N
% Pro:
0
0
0
0
10
10
0
0
0
10
0
10
0
10
0
% P
% Gln:
10
0
10
0
0
0
0
0
0
10
10
0
0
0
20
% Q
% Arg:
0
10
10
10
0
10
0
10
0
0
0
0
0
0
20
% R
% Ser:
0
20
0
0
10
10
10
40
30
10
0
30
10
0
0
% S
% Thr:
30
10
10
10
0
30
0
10
10
20
0
10
10
0
0
% T
% Val:
10
0
0
0
0
10
0
0
0
0
0
0
10
10
0
% V
% Trp:
0
0
10
0
0
0
0
0
0
0
10
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
10
10
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _