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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHSY1
All Species:
17.88
Human Site:
S522
Identified Species:
35.76
UniProt:
Q86X52
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X52
NP_055733.2
802
91784
S522
V
P
F
Q
L
P
G
S
K
S
E
H
K
E
P
Chimpanzee
Pan troglodytes
XP_523172
813
92793
S533
V
P
F
Q
L
P
G
S
K
S
E
H
K
E
P
Rhesus Macaque
Macaca mulatta
XP_001084554
583
67579
G323
N
I
L
I
P
L
S
G
R
F
D
M
F
V
R
Dog
Lupus familis
XP_545821
859
98336
S580
V
P
F
Q
L
P
G
S
K
N
E
H
K
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ11
800
91365
S521
V
A
F
Q
L
P
G
S
K
T
E
H
K
E
P
Rat
Rattus norvegicus
NP_001099738
788
89933
S510
V
P
F
Q
L
P
G
S
K
M
E
H
K
E
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506710
657
75412
K398
I
F
S
Q
Y
D
P
K
I
V
Y
S
G
K
V
Chicken
Gallus gallus
XP_413889
699
80960
R440
I
L
I
P
L
S
G
R
F
D
M
F
A
R
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997843
801
91813
P520
V
P
F
K
L
S
S
P
G
I
E
Q
H
E
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996440
832
95745
S517
S
S
H
F
T
M
P
S
G
L
L
S
P
T
Q
Honey Bee
Apis mellifera
XP_396991
814
93848
E536
L
N
L
N
F
N
F
E
E
V
D
P
V
K
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784554
785
89701
L503
N
S
D
A
S
S
Q
L
G
R
S
P
D
R
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
72.1
90.4
N.A.
94.3
92.8
N.A.
63.7
80.6
N.A.
77.6
N.A.
40.9
42.7
N.A.
44.2
Protein Similarity:
100
90.7
72.5
92.1
N.A.
97
95.3
N.A.
65.4
84.6
N.A.
88.9
N.A.
58.6
62
N.A.
63
P-Site Identity:
100
100
0
93.3
N.A.
86.6
93.3
N.A.
6.6
13.3
N.A.
46.6
N.A.
6.6
0
N.A.
0
P-Site Similarity:
100
100
13.3
100
N.A.
93.3
93.3
N.A.
20
20
N.A.
53.3
N.A.
6.6
26.6
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
9
0
0
0
9
17
0
9
0
9
% D
% Glu:
0
0
0
0
0
0
0
9
9
0
50
0
0
50
0
% E
% Phe:
0
9
50
9
9
0
9
0
9
9
0
9
9
0
9
% F
% Gly:
0
0
0
0
0
0
50
9
25
0
0
0
9
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
42
9
0
0
% H
% Ile:
17
9
9
9
0
0
0
0
9
9
0
0
0
0
9
% I
% Lys:
0
0
0
9
0
0
0
9
42
0
0
0
42
17
0
% K
% Leu:
9
9
17
0
59
9
0
9
0
9
9
0
0
0
0
% L
% Met:
0
0
0
0
0
9
0
0
0
9
9
9
0
0
0
% M
% Asn:
17
9
0
9
0
9
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
42
0
9
9
42
17
9
0
0
0
17
9
0
50
% P
% Gln:
0
0
0
50
0
0
9
0
0
0
0
9
0
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
9
9
0
0
0
17
9
% R
% Ser:
9
17
9
0
9
25
17
50
0
17
9
17
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
9
0
0
0
9
0
% T
% Val:
50
0
0
0
0
0
0
0
0
17
0
0
9
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _