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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHSY1 All Species: 17.88
Human Site: S522 Identified Species: 35.76
UniProt: Q86X52 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X52 NP_055733.2 802 91784 S522 V P F Q L P G S K S E H K E P
Chimpanzee Pan troglodytes XP_523172 813 92793 S533 V P F Q L P G S K S E H K E P
Rhesus Macaque Macaca mulatta XP_001084554 583 67579 G323 N I L I P L S G R F D M F V R
Dog Lupus familis XP_545821 859 98336 S580 V P F Q L P G S K N E H K E P
Cat Felis silvestris
Mouse Mus musculus Q6ZQ11 800 91365 S521 V A F Q L P G S K T E H K E P
Rat Rattus norvegicus NP_001099738 788 89933 S510 V P F Q L P G S K M E H K E P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506710 657 75412 K398 I F S Q Y D P K I V Y S G K V
Chicken Gallus gallus XP_413889 699 80960 R440 I L I P L S G R F D M F A R F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997843 801 91813 P520 V P F K L S S P G I E Q H E P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996440 832 95745 S517 S S H F T M P S G L L S P T Q
Honey Bee Apis mellifera XP_396991 814 93848 E536 L N L N F N F E E V D P V K D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784554 785 89701 L503 N S D A S S Q L G R S P D R I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.4 72.1 90.4 N.A. 94.3 92.8 N.A. 63.7 80.6 N.A. 77.6 N.A. 40.9 42.7 N.A. 44.2
Protein Similarity: 100 90.7 72.5 92.1 N.A. 97 95.3 N.A. 65.4 84.6 N.A. 88.9 N.A. 58.6 62 N.A. 63
P-Site Identity: 100 100 0 93.3 N.A. 86.6 93.3 N.A. 6.6 13.3 N.A. 46.6 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 20 20 N.A. 53.3 N.A. 6.6 26.6 N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 9 0 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 9 0 0 0 9 17 0 9 0 9 % D
% Glu: 0 0 0 0 0 0 0 9 9 0 50 0 0 50 0 % E
% Phe: 0 9 50 9 9 0 9 0 9 9 0 9 9 0 9 % F
% Gly: 0 0 0 0 0 0 50 9 25 0 0 0 9 0 0 % G
% His: 0 0 9 0 0 0 0 0 0 0 0 42 9 0 0 % H
% Ile: 17 9 9 9 0 0 0 0 9 9 0 0 0 0 9 % I
% Lys: 0 0 0 9 0 0 0 9 42 0 0 0 42 17 0 % K
% Leu: 9 9 17 0 59 9 0 9 0 9 9 0 0 0 0 % L
% Met: 0 0 0 0 0 9 0 0 0 9 9 9 0 0 0 % M
% Asn: 17 9 0 9 0 9 0 0 0 9 0 0 0 0 0 % N
% Pro: 0 42 0 9 9 42 17 9 0 0 0 17 9 0 50 % P
% Gln: 0 0 0 50 0 0 9 0 0 0 0 9 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 9 9 9 0 0 0 17 9 % R
% Ser: 9 17 9 0 9 25 17 50 0 17 9 17 0 0 0 % S
% Thr: 0 0 0 0 9 0 0 0 0 9 0 0 0 9 0 % T
% Val: 50 0 0 0 0 0 0 0 0 17 0 0 9 9 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _