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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CHSY1 All Species: 2.73
Human Site: S56 Identified Species: 5.45
UniProt: Q86X52 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X52 NP_055733.2 802 91784 S56 R S G Q A A A S Q A G G A R G
Chimpanzee Pan troglodytes XP_523172 813 92793 E62 S V E K S N R E Q A R G A V R
Rhesus Macaque Macaca mulatta XP_001084554 583 67579
Dog Lupus familis XP_545821 859 98336 A113 R P G Q A A A A S Q A G G A R
Cat Felis silvestris
Mouse Mus musculus Q6ZQ11 800 91365 Q56 R P G Q E A S Q P G G A R G D
Rat Rattus norvegicus NP_001099738 788 89933 G55 G A P G D A R G A Q L W P Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506710 657 75412
Chicken Gallus gallus XP_413889 699 80960 E20 K V E F F S S E G S D T S I P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_997843 801 91813 G56 G G C G G G G G M M M M M K K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_996440 832 95745 D53 T N L K T P A D I I G L R D E
Honey Bee Apis mellifera XP_396991 814 93848 S54 R L N V Y A S S M P G S R L L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_784554 785 89701 T54 R N D P F L S T P E P N H P S
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 89.4 72.1 90.4 N.A. 94.3 92.8 N.A. 63.7 80.6 N.A. 77.6 N.A. 40.9 42.7 N.A. 44.2
Protein Similarity: 100 90.7 72.5 92.1 N.A. 97 95.3 N.A. 65.4 84.6 N.A. 88.9 N.A. 58.6 62 N.A. 63
P-Site Identity: 100 26.6 0 46.6 N.A. 33.3 13.3 N.A. 0 0 N.A. 0 N.A. 13.3 26.6 N.A. 6.6
P-Site Similarity: 100 40 0 53.3 N.A. 40 26.6 N.A. 0 33.3 N.A. 6.6 N.A. 26.6 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 0 0 17 42 25 9 9 17 9 9 17 9 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 9 0 0 9 0 0 9 0 0 9 9 % D
% Glu: 0 0 17 0 9 0 0 17 0 9 0 0 0 0 9 % E
% Phe: 0 0 0 9 17 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 17 9 25 17 9 9 9 17 9 9 34 25 9 9 17 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 9 9 0 0 0 9 0 % I
% Lys: 9 0 0 17 0 0 0 0 0 0 0 0 0 9 9 % K
% Leu: 0 9 9 0 0 9 0 0 0 0 9 9 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 17 9 9 9 9 0 0 % M
% Asn: 0 17 9 0 0 9 0 0 0 0 0 9 0 0 0 % N
% Pro: 0 17 9 9 0 9 0 0 17 9 9 0 9 9 9 % P
% Gln: 0 0 0 25 0 0 0 9 17 17 0 0 0 9 0 % Q
% Arg: 42 0 0 0 0 0 17 0 0 0 9 0 25 9 17 % R
% Ser: 9 9 0 0 9 9 34 17 9 9 0 9 9 0 9 % S
% Thr: 9 0 0 0 9 0 0 9 0 0 0 9 0 0 0 % T
% Val: 0 17 0 9 0 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _