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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHSY1
All Species:
22.12
Human Site:
Y175
Identified Species:
44.24
UniProt:
Q86X52
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X52
NP_055733.2
802
91784
Y175
M
R
A
D
D
D
V
Y
I
K
G
D
R
L
E
Chimpanzee
Pan troglodytes
XP_523172
813
92793
Y186
M
R
A
D
D
D
V
Y
I
K
G
D
R
L
E
Rhesus Macaque
Macaca mulatta
XP_001084554
583
67579
R15
M
S
R
E
V
L
R
R
M
V
P
H
I
G
K
Dog
Lupus familis
XP_545821
859
98336
Y233
M
R
A
D
D
D
V
Y
I
K
G
D
R
L
E
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ11
800
91365
Y174
M
R
A
D
D
D
V
Y
I
K
G
D
R
L
E
Rat
Rattus norvegicus
NP_001099738
788
89933
E170
Y
I
K
G
D
R
L
E
S
F
L
R
S
L
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506710
657
75412
I90
K
D
D
L
Q
L
G
I
P
P
S
F
M
R
F
Chicken
Gallus gallus
XP_413889
699
80960
M132
S
R
E
V
L
R
R
M
V
P
H
I
G
E
C
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997843
801
91813
Y173
M
R
A
D
D
D
V
Y
I
K
S
E
K
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996440
832
95745
E165
Y
M
E
P
D
K
L
E
R
F
L
R
S
I
D
Honey Bee
Apis mellifera
XP_396991
814
93848
Y177
L
R
A
D
D
D
V
Y
V
R
T
D
R
L
E
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784554
785
89701
R166
D
R
M
E
T
F
L
R
S
L
N
S
S
H
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
72.1
90.4
N.A.
94.3
92.8
N.A.
63.7
80.6
N.A.
77.6
N.A.
40.9
42.7
N.A.
44.2
Protein Similarity:
100
90.7
72.5
92.1
N.A.
97
95.3
N.A.
65.4
84.6
N.A.
88.9
N.A.
58.6
62
N.A.
63
P-Site Identity:
100
100
6.6
100
N.A.
100
13.3
N.A.
0
6.6
N.A.
80
N.A.
6.6
73.3
N.A.
6.6
P-Site Similarity:
100
100
26.6
100
N.A.
100
20
N.A.
0
13.3
N.A.
93.3
N.A.
26.6
93.3
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
9
9
50
67
50
0
0
0
0
0
42
0
0
9
% D
% Glu:
0
0
17
17
0
0
0
17
0
0
0
9
0
9
50
% E
% Phe:
0
0
0
0
0
9
0
0
0
17
0
9
0
0
9
% F
% Gly:
0
0
0
9
0
0
9
0
0
0
34
0
9
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
9
9
0
9
0
% H
% Ile:
0
9
0
0
0
0
0
9
42
0
0
9
9
9
0
% I
% Lys:
9
0
9
0
0
9
0
0
0
42
0
0
9
0
9
% K
% Leu:
9
0
0
9
9
17
25
0
0
9
17
0
0
59
0
% L
% Met:
50
9
9
0
0
0
0
9
9
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
9
% N
% Pro:
0
0
0
9
0
0
0
0
9
17
9
0
0
0
0
% P
% Gln:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
67
9
0
0
17
17
17
9
9
0
17
42
9
0
% R
% Ser:
9
9
0
0
0
0
0
0
17
0
17
9
25
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
0
0
9
0
0
0
9
% T
% Val:
0
0
0
9
9
0
50
0
17
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
17
0
0
0
0
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _