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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CHSY1
All Species:
25.76
Human Site:
Y344
Identified Species:
51.52
UniProt:
Q86X52
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86X52
NP_055733.2
802
91784
Y344
E
I
V
L
M
S
K
Y
S
N
T
E
I
H
K
Chimpanzee
Pan troglodytes
XP_523172
813
92793
Y355
E
I
V
L
M
S
K
Y
S
N
T
E
I
H
K
Rhesus Macaque
Macaca mulatta
XP_001084554
583
67579
L165
E
F
L
T
G
K
Y
L
Y
S
A
V
D
G
Q
Dog
Lupus familis
XP_545821
859
98336
Y402
E
I
V
L
M
G
K
Y
S
N
T
E
I
H
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6ZQ11
800
91365
Y343
E
I
V
L
M
S
K
Y
S
S
T
E
I
Q
K
Rat
Rattus norvegicus
NP_001099738
788
89933
Y332
E
I
V
L
M
S
K
Y
S
S
T
E
I
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506710
657
75412
S240
S
G
S
L
S
F
L
S
N
S
L
K
M
F
V
Chicken
Gallus gallus
XP_413889
699
80960
Y282
F
L
T
G
K
Y
L
Y
S
G
A
D
G
Q
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_997843
801
91813
Y342
E
I
V
Q
M
S
R
Y
S
N
T
E
V
H
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_996440
832
95745
Y326
D
I
K
R
M
A
K
Y
L
E
V
P
D
E
S
Honey Bee
Apis mellifera
XP_396991
814
93848
Q345
D
I
Y
T
M
A
K
Q
L
G
I
R
V
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784554
785
89701
L324
E
I
Q
E
L
K
E
L
L
H
E
D
G
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
89.4
72.1
90.4
N.A.
94.3
92.8
N.A.
63.7
80.6
N.A.
77.6
N.A.
40.9
42.7
N.A.
44.2
Protein Similarity:
100
90.7
72.5
92.1
N.A.
97
95.3
N.A.
65.4
84.6
N.A.
88.9
N.A.
58.6
62
N.A.
63
P-Site Identity:
100
100
6.6
86.6
N.A.
86.6
86.6
N.A.
6.6
13.3
N.A.
73.3
N.A.
26.6
20
N.A.
13.3
P-Site Similarity:
100
100
26.6
86.6
N.A.
93.3
93.3
N.A.
33.3
26.6
N.A.
93.3
N.A.
40
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
17
0
0
0
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
0
0
0
0
0
0
0
0
0
0
17
17
0
0
% D
% Glu:
67
0
0
9
0
0
9
0
0
9
9
50
0
25
9
% E
% Phe:
9
9
0
0
0
9
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
9
0
9
9
9
0
0
0
17
0
0
17
9
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
34
0
% H
% Ile:
0
75
0
0
0
0
0
0
0
0
9
0
42
0
0
% I
% Lys:
0
0
9
0
9
17
59
0
0
0
0
9
0
0
34
% K
% Leu:
0
9
9
50
9
0
17
17
25
0
9
0
0
0
0
% L
% Met:
0
0
0
0
67
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
34
0
0
0
0
9
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
17
% P
% Gln:
0
0
9
9
0
0
0
9
0
0
0
0
0
25
9
% Q
% Arg:
0
0
0
9
0
0
9
0
0
0
0
9
0
0
9
% R
% Ser:
9
0
9
0
9
42
0
9
59
34
0
0
0
0
9
% S
% Thr:
0
0
9
17
0
0
0
0
0
0
50
0
0
0
0
% T
% Val:
0
0
50
0
0
0
0
0
0
0
9
9
17
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
0
9
9
67
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _