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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 19.7
Human Site: S180 Identified Species: 30.95
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 S180 G P M C E S N S T M P G P S L
Chimpanzee Pan troglodytes XP_001152578 327 35808 S180 G P M C E S N S T M P G P S L
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 S180 G P M C E S N S T M P G P S L
Dog Lupus familis XP_536134 334 36663 S187 G P M R E S N S T I P G P S L
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 Y176 G P M R E S N Y T K P G G T L
Rat Rattus norvegicus Q7TQ94 292 32072 L152 Y T M P G Y A L E P P V K T P
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 D136 S E T L S P G D S F S V F D T
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 S137 E T L S P G K S L S M F E T P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 N201 L L R K L G A N L L T Y P S A
Honey Bee Apis mellifera XP_397291 304 34596 G163 E S D Y V L P G Q K I E P P I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 S143 L D E R D C T S P G K T I V P
Poplar Tree Populus trichocarpa XP_002316330 293 31915 F153 R V Y K E S S F T E P G K D I
Maize Zea mays NP_001141322 288 31722 I148 F T A A G D T I V A V D S P F
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 G167 E K F Y F N P G D T G F K V F
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 S166 S P L G K L G S A I C Y D I R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 100 86.6 N.A. 66.6 13.3 N.A. N.A. N.A. 0 6.6 N.A. 13.3 6.6 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 73.3 20 N.A. N.A. N.A. 6.6 20 N.A. 26.6 13.3 N.A. 13.3
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 33.3 0 N.A. 0 13.3 N.A.
P-Site Similarity: 46.6 0 N.A. 6.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 14 0 7 7 0 0 0 0 7 % A
% Cys: 0 0 0 20 0 7 0 0 0 0 7 0 0 0 0 % C
% Asp: 0 7 7 0 7 7 0 7 7 0 0 7 7 14 0 % D
% Glu: 20 7 7 0 40 0 0 0 7 7 0 7 7 0 0 % E
% Phe: 7 0 7 0 7 0 0 7 0 7 0 14 7 0 14 % F
% Gly: 34 0 0 7 14 14 14 14 0 7 7 40 7 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 14 7 0 7 7 14 % I
% Lys: 0 7 0 14 7 0 7 0 0 14 7 0 20 0 0 % K
% Leu: 14 7 14 7 7 14 0 7 14 7 0 0 0 0 34 % L
% Met: 0 0 40 0 0 0 0 0 0 20 7 0 0 0 0 % M
% Asn: 0 0 0 0 0 7 34 7 0 0 0 0 0 0 0 % N
% Pro: 0 40 0 7 7 7 14 0 7 7 47 0 40 14 20 % P
% Gln: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % Q
% Arg: 7 0 7 20 0 0 0 0 0 0 0 0 0 0 7 % R
% Ser: 14 7 0 7 7 40 7 47 7 7 7 0 7 34 0 % S
% Thr: 0 20 7 0 0 0 14 0 40 7 7 7 0 20 7 % T
% Val: 0 7 0 0 7 0 0 0 7 0 7 14 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 7 14 0 7 0 7 0 0 0 14 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _