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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 20.3
Human Site: S186 Identified Species: 31.9
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 S186 N S T M P G P S L E S P V S T
Chimpanzee Pan troglodytes XP_001152578 327 35808 S186 N S T M P G P S L E S P V S T
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 S186 N S T M P G P S L E S P V S T
Dog Lupus familis XP_536134 334 36663 S193 N S T I P G P S L E S P V S T
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 T182 N Y T K P G G T L E P P V K T
Rat Rattus norvegicus Q7TQ94 292 32072 T158 A L E P P V K T P A G K V G L
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 D142 G D S F S V F D T P Y C K V G
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 T143 K S L S M F E T P Y C K V G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 S207 A N L L T Y P S A F T Y A T G
Honey Bee Apis mellifera XP_397291 304 34596 P169 P G Q K I E P P I S T P I G K
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 V149 T S P G K T I V P P V N T P V
Poplar Tree Populus trichocarpa XP_002316330 293 31915 D159 S F T E P G K D I V S V D S P
Maize Zea mays NP_001141322 288 31722 P154 T I V A V D S P F G R L G L T
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 V173 P G D T G F K V F Q T K F A K
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 I172 G S A I C Y D I R F P E F S L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 100 93.3 N.A. 60 13.3 N.A. N.A. N.A. 0 13.3 N.A. 13.3 13.3 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 66.6 20 N.A. N.A. N.A. 6.6 20 N.A. 40 33.3 N.A. 6.6
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 33.3 6.6 N.A. 0 13.3 N.A.
P-Site Similarity: 46.6 6.6 N.A. 20 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 14 0 7 7 0 0 0 0 7 7 0 0 7 7 0 % A
% Cys: 0 0 0 0 7 0 0 0 0 0 7 7 0 0 0 % C
% Asp: 0 7 7 0 0 7 7 14 0 0 0 0 7 0 0 % D
% Glu: 0 0 7 7 0 7 7 0 0 34 0 7 0 0 0 % E
% Phe: 0 7 0 7 0 14 7 0 14 14 0 0 14 0 0 % F
% Gly: 14 14 0 7 7 40 7 0 0 7 7 0 7 20 14 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 14 7 0 7 7 14 0 0 0 7 0 0 % I
% Lys: 7 0 0 14 7 0 20 0 0 0 0 20 7 7 14 % K
% Leu: 0 7 14 7 0 0 0 0 34 0 0 7 0 7 14 % L
% Met: 0 0 0 20 7 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 34 7 0 0 0 0 0 0 0 0 0 7 0 0 0 % N
% Pro: 14 0 7 7 47 0 40 14 20 14 14 40 0 7 7 % P
% Gln: 0 0 7 0 0 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % R
% Ser: 7 47 7 7 7 0 7 34 0 7 34 0 0 40 0 % S
% Thr: 14 0 40 7 7 7 0 20 7 0 20 0 7 7 40 % T
% Val: 0 0 7 0 7 14 0 14 0 7 7 7 47 7 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 7 0 0 0 14 0 0 0 7 7 7 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _