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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 16.97
Human Site: S192 Identified Species: 26.67
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 S192 P S L E S P V S T P A G K I G
Chimpanzee Pan troglodytes XP_001152578 327 35808 S192 P S L E S P V S T P A G K I G
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 S192 P S L E S P V S T P A G K V G
Dog Lupus familis XP_536134 334 36663 S199 P S L E S P V S T P A G K I G
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 K188 G T L E P P V K T P A G K V G
Rat Rattus norvegicus Q7TQ94 292 32072 G164 K T P A G K V G L A I C Y D M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 V148 F D T P Y C K V G V G I C Y D
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 G149 E T P Y C K V G V G I C Y D I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 T213 P S A F T Y A T G K A H W E I
Honey Bee Apis mellifera XP_397291 304 34596 G175 P P I S T P I G K L A L S I C
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 P155 I V P P V N T P V G K V G L G
Poplar Tree Populus trichocarpa XP_002316330 293 31915 S165 K D I V S V D S P V G R L G L
Maize Zea mays NP_001141322 288 31722 L160 S P F G R L G L T V C Y D L R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 A179 K V F Q T K F A K I G V A I C
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 S178 D I R F P E F S L K L R S M G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 93.3 100 N.A. 66.6 6.6 N.A. N.A. N.A. 0 6.6 N.A. 20 26.6 N.A. 6.6
P-Site Similarity: 100 100 100 100 N.A. 80 13.3 N.A. N.A. N.A. 0 13.3 N.A. 33.3 46.6 N.A. 13.3
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 13.3 6.6 N.A. 6.6 13.3 N.A.
P-Site Similarity: 20 13.3 N.A. 26.6 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 7 0 0 7 7 0 7 47 0 7 0 0 % A
% Cys: 0 0 0 0 7 7 0 0 0 0 7 14 7 0 14 % C
% Asp: 7 14 0 0 0 0 7 0 0 0 0 0 7 14 7 % D
% Glu: 7 0 0 34 0 7 0 0 0 0 0 0 0 7 0 % E
% Phe: 7 0 14 14 0 0 14 0 0 0 0 0 0 0 0 % F
% Gly: 7 0 0 7 7 0 7 20 14 14 20 34 7 7 47 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % H
% Ile: 7 7 14 0 0 0 7 0 0 7 14 7 0 34 14 % I
% Lys: 20 0 0 0 0 20 7 7 14 14 7 0 34 0 0 % K
% Leu: 0 0 34 0 0 7 0 7 14 7 7 7 7 14 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 7 % M
% Asn: 0 0 0 0 0 7 0 0 0 0 0 0 0 0 0 % N
% Pro: 40 14 20 14 14 40 0 7 7 34 0 0 0 0 0 % P
% Gln: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 7 0 7 0 0 0 0 0 0 14 0 0 7 % R
% Ser: 7 34 0 7 34 0 0 40 0 0 0 0 14 0 0 % S
% Thr: 0 20 7 0 20 0 7 7 40 0 0 0 0 0 0 % T
% Val: 0 14 0 7 7 7 47 7 14 20 0 14 0 14 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % W
% Tyr: 0 0 0 7 7 7 0 0 0 0 0 7 14 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _