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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 25.15
Human Site: S272 Identified Species: 39.52
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 S272 K R A S Y G H S M V V D P W G
Chimpanzee Pan troglodytes XP_001152578 327 35808 S272 K R A S Y G H S M V V D P W G
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 S272 K R A S Y G H S M V V D P W G
Dog Lupus familis XP_536134 334 36663 S279 K R A S Y G H S M V V D P W G
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 S268 T R A S Y G H S M V V D P W G
Rat Rattus norvegicus Q7TQ94 292 32072 P242 G H S M V V D P W G T V V A S
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 S226 W G H S T V V S P W G E V I A
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 P227 G H S S V I N P W G E V I S K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 V349 R C V V K G H V L V S T K R V
Honey Bee Apis mellifera XP_397291 304 34596 I254 S W G H A M V I D P W G S I I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 A233 K R A S Y G H A M I V D P W G
Poplar Tree Populus trichocarpa XP_002316330 293 31915 G243 N D K R E S Y G D T L I I D P
Maize Zea mays NP_001141322 288 31722 P238 G D S I I I D P W G T V I A R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 S268 Q I T F Y G T S F I A G P T G
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 S256 R R E S W G H S M V I D P W G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 100 100 N.A. 93.3 0 N.A. N.A. N.A. 13.3 6.6 N.A. 20 0 N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 93.3 6.6 N.A. N.A. N.A. 20 20 N.A. 33.3 0 N.A. 100
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 0 0 N.A. 33.3 73.3 N.A.
P-Site Similarity: 13.3 6.6 N.A. 46.6 93.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 40 0 7 0 0 7 0 0 7 0 0 14 7 % A
% Cys: 0 7 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 14 0 0 0 0 14 0 14 0 0 47 0 7 0 % D
% Glu: 0 0 7 0 7 0 0 0 0 0 7 7 0 0 0 % E
% Phe: 0 0 0 7 0 0 0 0 7 0 0 0 0 0 0 % F
% Gly: 20 7 7 0 0 60 0 7 0 20 7 14 0 0 54 % G
% His: 0 14 7 7 0 0 54 0 0 0 0 0 0 0 0 % H
% Ile: 0 7 0 7 7 14 0 7 0 14 7 7 20 14 7 % I
% Lys: 34 0 7 0 7 0 0 0 0 0 0 0 7 0 7 % K
% Leu: 0 0 0 0 0 0 0 0 7 0 7 0 0 0 0 % L
% Met: 0 0 0 7 0 7 0 0 47 0 0 0 0 0 0 % M
% Asn: 7 0 0 0 0 0 7 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 20 7 7 0 0 54 0 7 % P
% Gln: 7 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 14 47 0 7 0 0 0 0 0 0 0 0 0 7 7 % R
% Ser: 7 0 20 60 0 7 0 54 0 0 7 0 7 7 7 % S
% Thr: 7 0 7 0 7 0 7 0 0 7 14 7 0 7 0 % T
% Val: 0 0 7 7 14 14 14 7 0 47 40 20 14 0 7 % V
% Trp: 7 7 0 0 7 0 0 0 20 7 7 0 0 47 0 % W
% Tyr: 0 0 0 0 47 0 7 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _