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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NIT1 All Species: 15.76
Human Site: S40 Identified Species: 24.76
UniProt: Q86X76 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86X76 NP_005591.1 327 35896 S40 R P R A M A I S S S S C E L P
Chimpanzee Pan troglodytes XP_001152578 327 35808 S40 R P R A M A I S S S S C E L P
Rhesus Macaque Macaca mulatta XP_001115539 327 35953 S40 R P R A M A I S S S S C K L P
Dog Lupus familis XP_536134 334 36663 S47 S P R A M A I S S S S W E L P
Cat Felis silvestris
Mouse Mus musculus Q8VDK1 323 35677 W40 T M S S S T S W E L P L V A V
Rat Rattus norvegicus Q7TQ94 292 32072 K30 P N K Q E N F K T C A E L V Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q6INI7 276 30746 S14 S L V Q F L V S P V K S D N L
Zebra Danio Brachydanio rerio Q4VBV9 277 30347 K15 V V Q L H V S K I K A D N L G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O76464 460 52213 M40 A T I A V G Q M R S T S D K A
Honey Bee Apis mellifera XP_397291 304 34596 K40 Q M T S T N D K E K N L Q T V
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_790158 283 31389 E21 V C Q I T A T E D K V K T H D
Poplar Tree Populus trichocarpa XP_002316330 293 31915 T31 R V A A A Q M T S I N D L A A
Maize Zea mays NP_001141322 288 31722 A26 T S V G D V D A N Y A T C S R
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8VYF5 326 36438 L42 S L S S S L P L S N Y Q S L P
Baker's Yeast Sacchar. cerevisiae P47016 307 34674 V41 I Q K K A D V V F L P E A S D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 96.6 92.2 N.A. 83.7 76.7 N.A. N.A. N.A. 32.1 31.1 N.A. 34.7 47 N.A. 44.3
Protein Similarity: 100 99.6 99 95.2 N.A. 91.7 83.1 N.A. N.A. N.A. 49.8 49.2 N.A. 45.4 64.8 N.A. 63.6
P-Site Identity: 100 100 93.3 86.6 N.A. 0 0 N.A. N.A. N.A. 6.6 6.6 N.A. 13.3 0 N.A. 6.6
P-Site Similarity: 100 100 100 86.6 N.A. 6.6 26.6 N.A. N.A. N.A. 20 20 N.A. 33.3 26.6 N.A. 13.3
Percent
Protein Identity: 43.1 40.3 N.A. 28.7 33.3 N.A.
Protein Similarity: 61.4 56.5 N.A. 44.9 51.6 N.A.
P-Site Identity: 20 0 N.A. 20 0 N.A.
P-Site Similarity: 40 20 N.A. 33.3 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 40 14 34 0 7 0 0 20 0 7 14 14 % A
% Cys: 0 7 0 0 0 0 0 0 0 7 0 20 7 0 0 % C
% Asp: 0 0 0 0 7 7 14 0 7 0 0 14 14 0 14 % D
% Glu: 0 0 0 0 7 0 0 7 14 0 0 14 20 0 0 % E
% Phe: 0 0 0 0 7 0 7 0 7 0 0 0 0 0 0 % F
% Gly: 0 0 0 7 0 7 0 0 0 0 0 0 0 0 7 % G
% His: 0 0 0 0 7 0 0 0 0 0 0 0 0 7 0 % H
% Ile: 7 0 7 7 0 0 27 0 7 7 0 0 0 0 0 % I
% Lys: 0 0 14 7 0 0 0 20 0 20 7 7 7 7 0 % K
% Leu: 0 14 0 7 0 14 0 7 0 14 0 14 14 40 7 % L
% Met: 0 14 0 0 27 0 7 7 0 0 0 0 0 0 0 % M
% Asn: 0 7 0 0 0 14 0 0 7 7 14 0 7 7 0 % N
% Pro: 7 27 0 0 0 0 7 0 7 0 14 0 0 0 34 % P
% Gln: 7 7 14 14 0 7 7 0 0 0 0 7 7 0 7 % Q
% Arg: 27 0 27 0 0 0 0 0 7 0 0 0 0 0 7 % R
% Ser: 20 7 14 20 14 0 14 34 40 34 27 14 7 14 0 % S
% Thr: 14 7 7 0 14 7 7 7 7 0 7 7 7 7 0 % T
% Val: 14 14 14 0 7 14 14 7 0 7 7 0 7 7 14 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 7 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 7 7 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _